Michael Tayao
Overview
Explore the profile of Michael Tayao including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
106
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0
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Recent Articles
1.
Chambers C, Watakul S, Schofield P, Howell A, Zhu J, Tran A, et al.
Sci Adv
. 2025 Mar;
11(11):eadq4416.
PMID: 40073121
Pancreatic cancer (PC) is a highly metastatic malignancy. More than 80% of patients with PC present with advanced-stage disease, preventing potentially curative surgery. The neuropeptide Y (NPY) system, best known...
2.
Pereira B, Ritchie S, Chambers C, Gordon K, Magenau A, Murphy K, et al.
Sci Adv
. 2024 Jul;
10(27):eadl1197.
PMID: 38959305
Pancreatic ductal adenocarcinoma (PDAC) is characterized by increasing fibrosis, which can enhance tumor progression and spread. Here, we undertook an unbiased temporal assessment of the matrisome of the highly metastatic...
3.
Filipe E, Velayuthar S, Philp A, Nobis M, Latham S, Parker A, et al.
Adv Sci (Weinh)
. 2024 Apr;
11(23):e2307963.
PMID: 38602451
In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary tumor biomechanics on the latter...
4.
Chitty J, Yam M, Perryman L, Parker A, Skhinas J, Setargew Y, et al.
Nat Cancer
. 2023 Aug;
4(9):1326-1344.
PMID: 37640930
The lysyl oxidase family represents a promising target in stromal targeting of solid tumors due to the importance of this family in crosslinking and stabilizing fibrillar collagens and its known...
5.
Ballinger M, Pattnaik S, Mundra P, Zaheed M, Rath E, Priestley P, et al.
Science
. 2023 Jan;
379(6629):253-260.
PMID: 36656928
Cancer genetics has to date focused on epithelial malignancies, identifying multiple histotype-specific pathways underlying cancer susceptibility. Sarcomas are rare malignancies predominantly derived from embryonic mesoderm. To identify pathways specific to...
6.
Murphy K, Reed D, Vennin C, Conway J, Nobis M, Yin J, et al.
Sci Adv
. 2021 Sep;
7(40):eabh0363.
PMID: 34586840
Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic, chemoresistant malignancy and is characterized by a dense, desmoplastic stroma that modulates PDAC progression. Here, we visualized transient manipulation of focal adhesion...
7.
Floerchinger A, Murphy K, Latham S, Warren S, McCulloch A, Lee Y, et al.
Cell Rep
. 2021 Sep;
36(11):109689.
PMID: 34525350
Assessing drug response within live native tissue provides increased fidelity with regards to optimizing efficacy while minimizing off-target effects. Here, using longitudinal intravital imaging of a Rac1-Förster resonance energy transfer...
8.
Chitty J, Skhinas J, Filipe E, Wang S, Cupello C, Grant R, et al.
Cancer Rep (Hoboken)
. 2020 Jul;
3(1):e1209.
PMID: 32671954
Background: The use of in vitro cell cultures is a powerful tool for obtaining key insights into the behaviour and response of cells to interventions in normal and disease situations....
9.
Tayao M, Andrici J, Farzin M, Clarkson A, Sioson L, Watson N, et al.
PLoS One
. 2016 Mar;
11(3):e0150338.
PMID: 26982343
Background: Pancreatic cancer is both common and highly lethal and therefore new biomarkers or potential targets for treatment are needed. Loss of BRCA associated protein-1 (BAP1) expression has been found...
10.
Andrici J, Goeppert B, Sioson L, Clarkson A, Renner M, Stenzinger A, et al.
Medicine (Baltimore)
. 2016 Jan;
95(2):e2491.
PMID: 26765459
BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that functions as a tumor suppressor gene. Double hit BAP1 inactivation has been reported in a range of tumor types, including intrahepatic...