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Michael Sefton

Explore the profile of Michael Sefton including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 141
Followers 0
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Recent Articles
1.
Li H, Chang L, Du W, Gupta S, Khorshidi A, Sefton M, et al.
Mol Ther . 2025 Jan; 33(1):415. PMID: 39794096
No abstract available.
2.
Grattoni A, Korbutt G, Tomei A, Garcia A, Pepper A, Stabler C, et al.
Nat Rev Endocrinol . 2024 Sep; 21(1):14-30. PMID: 39227741
Type 1 diabetes mellitus (T1DM) is a growing global health concern that affects approximately 8.5 million individuals worldwide. T1DM is characterized by an autoimmune destruction of pancreatic β cells, leading...
3.
Talior-Volodarsky I, Mahou R, Zhang D, Sefton M
Biomaterials . 2017 Aug; 144:199-210. PMID: 28841464
The IGF-1 signaling pathway and IGF-1-dependent macrophage/endothelial cell crosstalk was found to be critical features of the vascular regenerative effect displayed by implanted methacrylic acid -co-isodecyl acrylate (MAA-co-IDA; 40% MAA)...
4.
Li H, Chang L, Du W, Gupta S, Khorshidi A, Sefton M, et al.
Mol Ther . 2014 Jun; 22(10):1839-50. PMID: 24954475
Delayed or impaired wound healing is a major public health issue worldwide, especially in patients with diabetes mellitus and vascular atherosclerosis. MicroRNAs have been identified as key regulators of wound...
5.
Du W, Fang L, Li M, Yang X, Liang Y, Peng C, et al.
J Cell Sci . 2013 Feb; 126(Pt 6):1440-53. PMID: 23418360
MicroRNAs are known to play regulatory roles in gene expression associated with cancer development. We analyzed levels of the microRNA miR-24 in patients with breast carcinoma and found that miR-24...
6.
Holladay C, Power K, Sefton M, OBrien T, Gallagher W, Pandit A
Mol Ther . 2011 Jan; 19(5):969-78. PMID: 21266957
While stem cell transplantation could potentially treat a variety of disorders, clinical studies have not yet demonstrated conclusive benefits. This may be partly because transplanted stem cells have low survival...