Michael Sammeth
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Explore the profile of Michael Sammeth including associated specialties, affiliations and a list of published articles.
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42
Citations
7106
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Recent Articles
11.
Brant A, Menezes A, Felix S, de Almeida L, Sammeth M, Moreira M
Genomics
. 2018 Dec;
111(6):1853-1861.
PMID: 30552977
Scarce data are available on the expression of papillomavirus genome and the frequency of alternatively spliced E6E7 mRNAs in invasive cervical cancer. We carried out a comprehensive characterization of HPV...
12.
Brito T, Julio A, Berni M, de Castro Poncio L, Bernardes E, Araujo H, et al.
PLoS Negl Trop Dis
. 2018 Oct;
12(10):e0006760.
PMID: 30303955
The piRNA pathway is a surveillance system that guarantees oogenesis and adult fertility in a range of animal species. The pathway is centered on PIWI clade Argonaute proteins and the...
13.
Coelho V, Sammeth M
Bioinformatics
. 2018 Jun;
34(22):3809-3816.
PMID: 29868795
Motivation: Alternative splicing (AS) has been demonstrated to play a role in shaping eukaryotic gene diversity at the transcriptional level. However, the impact of AS on the proteome is still...
14.
Boroni M, Sammeth M, Gava S, Jorge N, Macedo A, Machado C, et al.
Sci Rep
. 2018 Mar;
8(1):3877.
PMID: 29497070
Spliced leader dependent trans-splicing (SLTS) has been described as an important RNA regulatory process that occurs in different organisms, including the trematode Schistosoma mansoni. We identified more than seven thousand...
15.
Ferreira P, Munoz-Aguirre M, Reverter F, Sa Godinho C, Sousa A, Amadoz A, et al.
Nat Commun
. 2018 Feb;
9(1):490.
PMID: 29440659
Post-mortem tissues samples are a key resource for investigating patterns of gene expression. However, the processes triggered by death and the post-mortem interval (PMI) can significantly alter physiologically normal RNA...
16.
Oti M, Sammeth M
Methods Mol Biol
. 2017 Dec;
1704:451-472.
PMID: 29277878
Genomes can be compared at different levels of divergence, either between species or within species. Within species genomes can be compared between different subpopulations, such as human subpopulations from different...
17.
Oti M, Pane A, Sammeth M
Methods Mol Biol
. 2017 Dec;
1704:433-450.
PMID: 29277877
Since the pioneering studies of Thomas Hunt Morgan and coworkers at the dawn of the twentieth century, Drosophila melanogaster and its sister species have tremendously contributed to unveil the rules...
18.
Schwartze V, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, et al.
PLoS Genet
. 2016 Dec;
12(12):e1006491.
PMID: 27918580
[This corrects the article DOI: 10.1371/journal.pgen.1004496.].
19.
Ferreira P, Oti M, Barann M, Wieland T, Ezquina S, Friedlander M, et al.
Sci Rep
. 2016 Sep;
6:32406.
PMID: 27617755
Recent advances in the cost-efficiency of sequencing technologies enabled the combined DNA- and RNA-sequencing of human individuals at the population-scale, making genome-wide investigations of the inter-individual genetic impact on gene...
20.
Rivas M, Pirinen M, Conrad D, Lek M, Tsang E, Karczewski K, et al.
Science
. 2015 May;
348(6235):666-9.
PMID: 25954003
Accurate prediction of the functional effect of genetic variation is critical for clinical genome interpretation. We systematically characterized the transcriptome effects of protein-truncating variants, a class of variants expected to...