Michael S Toss
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Explore the profile of Michael S Toss including associated specialties, affiliations and a list of published articles.
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99
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966
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Recent Articles
1.
Katayama A, Makhlouf S, Toss M, Oyama T, Rakha E
Histopathology
. 2024 Dec;
86(5):813-823.
PMID: 39654376
Background And Aims: Lobular carcinoma (LC) of the breast exhibits diverse morphology and clinical behaviour. The pleomorphic variant (pLC) displays distinct cytonuclear features and aggressiveness compared to the classic variant...
2.
Ibrahim A, Atallah N, Makhlouf S, Toss M, Green A, Rakha E
Cancers (Basel)
. 2024 Nov;
16(22).
PMID: 39594769
Background: Assembly factor for spindle microtubules (ASPM) has gained significant attention in cancer research due to its association with tumor growth and progression. Through the analysis of large-scale genomic datasets,...
3.
Lashen A, Toss M, Rutland C, Green A, Mongan N, Rakha E
Pathobiology
. 2024 Aug;
92(1):18-27.
PMID: 39191229
Introduction: Minichromosome maintenance complex component 7 (MCM7) plays an essential role in proliferation and DNA replication of cancer cells. However, the expression and prognostic significance of MCM7 in breast cancer...
4.
Woodcock C, Alsaleem M, Toss M, Lothion-Roy J, Harris A, Jeyapalan J, et al.
Discov Oncol
. 2024 Aug;
15(1):343.
PMID: 39127986
Background: N6-methyladenosine (mA) is the most common internal RNA modification and is involved in regulation of RNA and protein expression. AlkB family member 5 (ALKBH5) is a mA demethylase. Given...
5.
Ibrahim A, Jahanifar M, Wahab N, Toss M, Makhlouf S, Atallah N, et al.
Mod Pathol
. 2023 Dec;
37(3):100416.
PMID: 38154653
In recent years, artificial intelligence (AI) has demonstrated exceptional performance in mitosis identification and quantification. However, the implementation of AI in clinical practice needs to be evaluated against the existing...
6.
Ibrahim A, Toss M, Alsaleem M, Makhlouf S, Atallah N, Green A, et al.
Mod Pathol
. 2023 Dec;
37(2):100403.
PMID: 38104894
The use of proliferation markers provides valuable information about the rate of tumor growth, which can guide treatment decisions. However, there is still a lack of consensus regarding the optimal...
7.
Aljohani A, Alsaeed S, Toss M, Raafat S, Green A, Rakha E
Am J Cancer Res
. 2023 Dec;
13(11):5334-5351.
PMID: 38058796
Lymphovascular invasion (LVI) is a common phenomenon in breast cancer (BC), and it is correlated to poor outcome. However, the biomarkers that influence the development of LVI remain to be...
8.
Atallah N, Haque M, Quinn C, Toss M, Makhlouf S, Ibrahim A, et al.
Eur J Cancer
. 2023 Oct;
195:113371.
PMID: 37897865
Background: Breast cancer (BC) expressing low levels of human epidermal growth factor receptor 2 (HER2 Low) is an emerging category that needs further refining. This study aims to provide a...
9.
Alblihy A, Ali R, Algethami M, Ritchie A, Shoqafi A, Alqahtani S, et al.
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37446144
The MRE11 nuclease is essential during DNA damage recognition, homologous recombination, and replication. BRCA2 plays important roles during homologous recombination and replication. Here, we show that effecting an MRE11 blockade...
10.
Atallah N, Wahab N, Toss M, Makhlouf S, Ibrahim A, Lashen A, et al.
Mod Pathol
. 2023 Jun;
36(10):100254.
PMID: 37380057
Tumor-associated stroma in breast cancer (BC) is complex and exhibits a high degree of heterogeneity. To date, no standardized assessment method has been established. Artificial intelligence (AI) could provide an...