Chitra Joseph
Overview
Explore the profile of Chitra Joseph including associated specialties, affiliations and a list of published articles.
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48
Citations
1020
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Recent Articles
1.
McWilliams D, Shahtaheri M, Koushesh S, Joseph C, Gowler P, Xu L, et al.
Osteoarthr Cartil Open
. 2024 Dec;
7(1):100544.
PMID: 39717525
Objectives: Histological osteochondral characteristics of inflammation, fibrosis, vascularity, cartilage islands, vessels entering cartilage, thickened trabeculae and cysts are associated with bone marrow lesions (BMLs) in human knee osteoarthritis (OA). We...
2.
Goodwin A, John A, Joseph C, Habgood A, Tatler A, Susztak K, et al.
Development
. 2023 Apr;
150(9).
PMID: 37102682
Alveolar development and repair require tight spatiotemporal regulation of numerous signalling pathways that are influenced by chemical and mechanical stimuli. Mesenchymal cells play key roles in numerous developmental processes. Transforming...
3.
Oldham J, Allen R, Lorenzo-Salazar J, Molyneaux P, Ma S, Joseph C, et al.
Am J Respir Crit Care Med
. 2023 Feb;
207(11):1515-1524.
PMID: 36780644
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by limited treatment options and high mortality. A better understanding of the molecular drivers of IPF progression is needed. To identify...
4.
Kariri Y, Joseph C, Alsaleem M, Elsharawy K, Alsaeed S, Toss M, et al.
Cancers (Basel)
. 2022 Nov;
14(22).
PMID: 36428736
Background: Cell Division Cycle Associated 5 () plays a role in the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signalling pathway involving cell division, cancer cell migration and apoptosis. This study aims to assess...
5.
Joseph C, Tatler A
J Asthma Allergy
. 2022 May;
15:595-610.
PMID: 35592385
Airway remodeling is a complex clinical feature of asthma that involves long-term disruption and modification of airway architecture, which contributes significantly to airway hyperresponsiveness (AHR) and lung function decline. It...
6.
Kanugovi Vijayavittal A, Kumar P, Sugunan S, Joseph C, Devaki B, Paithankar K, et al.
Biochem Biophys Res Commun
. 2022 Feb;
600:44-50.
PMID: 35182974
The heat shock transcription factor HSF1 regulates the inducible Hsp gene transcription, whereas HSF2 is involved in the constitutive transcription. HSFs can work for the non-heat shock genes transcription in...
7.
Kariri Y, Toss M, Alsaleem M, Elsharawy K, Joseph C, Mongan N, et al.
Breast Cancer Res Treat
. 2022 Feb;
192(3):529-539.
PMID: 35124721
Background: The Ubiquitin-conjugating enzyme 2C (UBE2C) is essential for the ubiquitin-proteasome system and is involved in cancer cell migration and apoptosis. This study aimed to determine the prognostic value of...
8.
Althobiti M, El-Sharawy K, Joseph C, Aleskandarany M, Toss M, Green A, et al.
Breast Cancer Res Treat
. 2021 Aug;
189(3):621-630.
PMID: 34453638
Purpose: The outcome of the luminal oestrogen receptor-positive (ER +) subtype of breast cancer (BC) is highly variable and patient stratification needs to be refined. We assessed the prognostic significance...
9.
Bui L, Winters N, Chung M, Joseph C, Gutierrez A, Habermann A, et al.
Nat Commun
. 2021 Jul;
12(1):4314.
PMID: 34262047
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 (COVID-19) and poor outcomes. Here, we analyze the transcriptomes of 611,398 single cells isolated from healthy...
10.
John A, Joseph C, Jenkins G, Tatler A
Immunol Rev
. 2021 May;
302(1):228-240.
PMID: 34028807
The COVID-19 pandemic rapidly spread around the world following the first reports in Wuhan City, China in late 2019. The disease, caused by the novel SARS-CoV-2 virus, is primarily a...