Michael R Schon
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Explore the profile of Michael R Schon including associated specialties, affiliations and a list of published articles.
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61
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3553
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Recent Articles
11.
Knoblich T, Hinz U, Stravodimos C, Schon M, Mehrabi A, Buchler M, et al.
BMC Surg
. 2020 Jan;
20(1):19.
PMID: 31996202
Background: Indications for liver surgery are expanding fast and complexity of procedures increases. Preoperative mortality risk assessment by scoring systems is debatable. A previously published externally validated Mortality Risk Score...
12.
Langhardt J, Flehmig G, Kloting N, Lehmann S, Ebert T, Kern M, et al.
Obes Facts
. 2018 Dec;
11(6):475-490.
PMID: 30537708
Background/aims: Altered expression and circulating levels of glutathione peroxidase 3 (GPX3) have been observed in obesity and type 2 diabetes (T2D) across species. Here, we investigate whether GPX3 serum concentrations...
13.
Giusepponi M, Kern M, Chakaroun R, Wohland T, Kovacs P, Dietrich A, et al.
Biochem Biophys Res Commun
. 2018 Oct;
505(3):801-806.
PMID: 30297106
The aim of the study was to identify and functionally characterize novel candidate gene/s involved in the development of resistance to diet-induced obesity in rats. In a high-fat-diet (HFD) study...
14.
Hoffmann K, Hinz U, Stravodimos C, Knoblich T, Schon M, Buchler M, et al.
Surgery
. 2018 Aug;
164(5):998-1005.
PMID: 30107885
Background: In recent years, the profile for patients undergoing complex liver resections has changed, with mortality rates remaining generally stable. With these factors in mind, the objective of this study...
15.
Keller M, Klos M, Rohde K, Kruger J, Kurze T, Dietrich A, et al.
FASEB J
. 2018 Jun;
:fj201800528R.
PMID: 29932866
DNA methylation is a crucial epigenetic mechanism in obesity and fat distribution. We explored the Sarcospan ( SSPN) gene locus by using genome-wide data sets comprising methylation and expression data,...
16.
Justinger C, Gruden J, Kouladouros K, Stravodimos C, Reimer P, Tannapfel A, et al.
J Surg Oncol
. 2018 Feb;
117(5):1084-1091.
PMID: 29448307
Background: Selective internal radiotherapy (SIRT) has emerged as an effective therapy for patients with liver malignancies. Here, we report our analysis of histopathological changes in tumors and healthy liver tissue...
17.
Rohde K, Klos M, Hopp L, Liu X, Keller M, Stumvoll M, et al.
Sci Rep
. 2017 Sep;
7(1):12369.
PMID: 28959056
The SNP variant rs2943650 near IRS1 gene locus was previously associated with decreased body fat and IRS1 gene expression as well as an adverse metabolic profile in humans. Here, we...
18.
Keller M, Hopp L, Liu X, Wohland T, Rohde K, Cancello R, et al.
Mol Metab
. 2017 Jan;
6(1):86-100.
PMID: 28123940
Objective/methods: DNA methylation plays an important role in obesity and related metabolic complications. We examined genome-wide DNA promoter methylation along with mRNA profiles in paired samples of human subcutaneous adipose...
19.
Pfeiffer S, Kruger J, Maierhofer A, Bottcher Y, Kloting N, El Hajj N, et al.
Sci Rep
. 2016 Jun;
6:27969.
PMID: 27346320
Recently, a genome-wide analysis identified DNA methylation of the HIF3A (hypoxia-inducible factor 3A) as strongest correlate of BMI. Here we tested the hypothesis that HIF3A mRNA expression and CpG-sites methylation...
20.
Brune J, Kern M, Kunath A, Flehmig G, Schon M, Lohmann T, et al.
Obesity (Silver Spring)
. 2015 Dec;
24(1):51-9.
PMID: 26647900
Objective: Independent previous studies in both rodents and humans suggest a role of developmental genes in the origin of obesity and body fat distribution. Here, the hypothesis that human adipose...