Tobias Lohmann
Overview
Explore the profile of Tobias Lohmann including associated specialties, affiliations and a list of published articles.
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38
Citations
1003
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Recent Articles
1.
Sun C, Holstein D, Garcia-Cubero N, Moulla Y, Stroh C, Dietrich A, et al.
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38069170
In previous genome-wide association studies (GWAS), genetic loci associated with obesity and impaired fat distribution (FD) have been identified. In the present study, we elucidated the role of the gene,...
2.
Molder J, Guiu-Jurado E, Moulla Y, Stroh C, Dietrich A, Schon M, et al.
Genes (Basel)
. 2023 Feb;
14(2).
PMID: 36833305
The SNP rs10487505 in the promotor region of the gene was reported to be associated with decreased circulating leptin and increased body mass index (BMI). However, the phenotypic outcomes affected...
3.
Sun C, Forster F, Gutsmann B, Moulla Y, Stroh C, Dietrich A, et al.
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955692
locus has been shown to be associated with body fat distribution (FD), but neither the causal gene nor its role in metabolic diseases has been elucidated. We hypothesize that may...
4.
Steenblock C, Hassanein M, Khan E, Yaman M, Kamel M, Barbir M, et al.
Horm Metab Res
. 2022 Jun;
54(8):496-502.
PMID: 35724688
Obesity is an increasing health problem all over the world. In combination with the current COVID-19 pandemic, this has turned into a massive challenge as individuals with overweight and obesity...
5.
Milek M, Moulla Y, Kern M, Stroh C, Dietrich A, Schon M, et al.
Int J Mol Sci
. 2022 Feb;
23(4).
PMID: 35216336
(1) Adipsin is an adipokine that may link increased fat mass and adipose tissue dysfunction to obesity-related cardiometabolic diseases. Here, we investigated whether adipsin serum concentrations and adipose tissue (AT)...
6.
Langhardt J, Flehmig G, Kloting N, Lehmann S, Ebert T, Kern M, et al.
Obes Facts
. 2018 Dec;
11(6):475-490.
PMID: 30537708
Background/aims: Altered expression and circulating levels of glutathione peroxidase 3 (GPX3) have been observed in obesity and type 2 diabetes (T2D) across species. Here, we investigate whether GPX3 serum concentrations...
7.
Keller M, Klos M, Rohde K, Kruger J, Kurze T, Dietrich A, et al.
FASEB J
. 2018 Jun;
:fj201800528R.
PMID: 29932866
DNA methylation is a crucial epigenetic mechanism in obesity and fat distribution. We explored the Sarcospan ( SSPN) gene locus by using genome-wide data sets comprising methylation and expression data,...
8.
Rohde K, Klos M, Hopp L, Liu X, Keller M, Stumvoll M, et al.
Sci Rep
. 2017 Sep;
7(1):12369.
PMID: 28959056
The SNP variant rs2943650 near IRS1 gene locus was previously associated with decreased body fat and IRS1 gene expression as well as an adverse metabolic profile in humans. Here, we...
9.
Keller M, Hopp L, Liu X, Wohland T, Rohde K, Cancello R, et al.
Mol Metab
. 2017 Jan;
6(1):86-100.
PMID: 28123940
Objective/methods: DNA methylation plays an important role in obesity and related metabolic complications. We examined genome-wide DNA promoter methylation along with mRNA profiles in paired samples of human subcutaneous adipose...
10.
Pfeiffer S, Kruger J, Maierhofer A, Bottcher Y, Kloting N, El Hajj N, et al.
Sci Rep
. 2016 Jun;
6:27969.
PMID: 27346320
Recently, a genome-wide analysis identified DNA methylation of the HIF3A (hypoxia-inducible factor 3A) as strongest correlate of BMI. Here we tested the hypothesis that HIF3A mRNA expression and CpG-sites methylation...