Michael R Murphy
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Explore the profile of Michael R Murphy including associated specialties, affiliations and a list of published articles.
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34
Citations
4711
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Recent Articles
1.
Murphy M, Ganapathi M, Lee T, Fisher J, Patel M, Jayakar P, et al.
bioRxiv
. 2025 Jan;
PMID: 39803500
The heart employs a specialized ribosome in its muscle cells to translate genetic information into proteins, a fundamental adaptation with an elusive physiological role. Its significance is underscored by the...
2.
Goldfarb T, Kodali V, Pujar S, Brover V, Robbertse B, Farrell C, et al.
Nucleic Acids Res
. 2024 Nov;
53(D1):D243-D257.
PMID: 39526381
Reference sequences and annotations serve as the foundation for many lines of research today, from organism and sequence identification to providing a core description of the genes, transcripts and proteins...
3.
Murphy M, Ramadei A, Doymaz A, Varriano S, Natelson D, Yu A, et al.
Nucleic Acids Res
. 2023 Oct;
51(21):11911-11926.
PMID: 37870464
Alternative Polyadenylation (APA) is an emerging mechanism for dynamic changes in gene expression. Previously, we described widespread APA occurrence in introns during the DNA damage response (DDR). Here, we show...
4.
Kesner J, Chen Z, Shi P, Aparicio A, Murphy M, Guo Y, et al.
Nature
. 2023 Apr;
617(7960):395-402.
PMID: 37046090
Translation is pervasive outside of canonical coding regions, occurring in long noncoding RNAs, canonical untranslated regions and introns, especially in ageing, neurodegeneration and cancer. Notably, the majority of tumour-specific antigens...
5.
Shi P, Murphy M, Aparicio A, Kesner J, Fang Z, Chen Z, et al.
Commun Biol
. 2023 Mar;
6(1):334.
PMID: 36977923
CRISPR/Cas13 systems are increasingly used for programmable targeting of RNAs. While Cas13 nucleases are capable of degrading both target RNAs and bystander RNAs in vitro and in bacteria, initial studies...
6.
Murphy M, Ramadei A, Doymaz A, Varriano S, Natelson D, Yu A, et al.
bioRxiv
. 2023 Jan;
PMID: 36711808
Alternative Polyadenylation (APA) is an emerging mechanism for dynamic changes in gene expression. Previously, we described widespread APA occurrence in introns during the DNA damage response (DDR). Here, we show...
7.
Knollinger S, Poczynek M, Miller B, Mueller I, de Almeida R, Murphy M, et al.
Animals (Basel)
. 2022 Sep;
12(18).
PMID: 36139305
Fifteen multiparous rumen-cannulated Holstein cows were assigned to one of five treatments in a replicated 5 × 5 Latin square design. The treatments were low-starch (LS) (22.8 ± 1% of...
8.
Mendes A, Murphy M, Casper D, Erickson P
Transl Anim Sci
. 2022 Jul;
6(3):txac080.
PMID: 35795071
Commercial dairy producers may get frustrated by the lower ratio of female to male calves born because female calves are more valuable than bull calves. Our objective was to determine...
9.
Morales J, Pujar S, Loveland J, Astashyn A, Bennett R, Berry A, et al.
Nature
. 2022 Apr;
604(7905):310-315.
PMID: 35388217
Comprehensive genome annotation is essential to understand the impact of clinically relevant variants. However, the absence of a standard for clinical reporting and browser display complicates the process of consistent...
10.
Murphy M, Hannon B
Math Biosci Eng
. 2021 Sep;
18(5):6806-6818.
PMID: 34517558
Our goal was to examine how total, average (heat production rate per unit mass) and marginal (the increase in the heat production rate per unit increase in mass) rates of...