Michael R Franklin
Overview
Explore the profile of Michael R Franklin including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
31
Citations
258
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Larson E, Pond C, Rai P, Matainaho T, Piskaut P, Franklin M, et al.
Evid Based Complement Alternat Med
. 2016 Sep;
2016:7869710.
PMID: 27642356
The hypothesis underlying this current work is that fresh juice expressed from Papua New Guinea (PNG) medicinal plants (succus) will inhibit human Cytochrome P450s (CYPs). The CYP inhibitory activity identified...
2.
Bergonia H, Franklin M, Kushner J, Phillips J
Clin Biochem
. 2015 May;
48(12):788-95.
PMID: 25959086
Objective: In mammalian cells the rate-limiting step in heme biosynthesis is the formation of δ-aminolevulinic acid (ALA). The reaction intermediates, porphyrins and iron and the final product, heme can be...
3.
Larson E, Hathaway L, Lamb J, Pond C, Rai P, Matainaho T, et al.
J Ethnopharmacol
. 2014 Aug;
155(3):1433-40.
PMID: 25138353
Ethnopharmacological Relevance: A substantial proportion of the population in Papua New Guinea (PNG) lives with human immunodeficiency virus (HIV). Treatment requires lifelong use of antiretroviral therapy (ART). The majority of...
4.
Bolton J, Reilly C, Franklin M
Chem Res Toxicol
. 2014 Jul;
27(8):1327.
PMID: 25068804
No abstract available.
5.
Kuzbari O, Peterson C, Franklin M, Hathaway L, Johnstone E, Hammoud A, et al.
Reprod Toxicol
. 2013 Feb;
37:24-30.
PMID: 23384967
Bisphenol A (BPA) and diethylstilbestrol (DES) are endocrine-disrupting chemicals that interact with the human pregnane X receptor (PXR). CYP3A4 enzyme is essential in the hydroxylation of steroid hormones and is...
6.
Poerschke R, Franklin M, Bild A, Moos P
J Biochem Mol Toxicol
. 2012 Jul;
26(9):344-53.
PMID: 22807314
Cytoprotective enzyme elevation through the nuclear erythroid 2 p45-related factor 2 (Nrf2)-Kelch-like ECH-associated protein 1/antioxidant response element pathway has been promulgated for cancer prevention. This study compares the redox insult...
7.
Ali A, Dua Y, Constance J, Franklin M, Dudek F
Epilepsia
. 2011 Nov;
53(1):199-206.
PMID: 22092257
Purpose: Convenient and effective methods for administering potential antiepileptic drugs (AEDs) chronically should facilitate many experiments in animal models of chronic epilepsy with spontaneous recurrent seizures. This proof-of-principle study aimed...
8.
Phillips J, Kushner J, Bergonia H, Franklin M
Blood Cells Mol Dis
. 2011 Sep;
47(4):249-54.
PMID: 21880518
Cytochrome P4501A2 (Cyp1a2) is important in the development of uroporphyria in mice, a model of porphyria cutanea tarda in humans. Heretofore, mice homozygous for the Cyp1a2-/- mutation do not develop...
9.
Franklin M, Phillips J, Kushner J
Environ Toxicol Pharmacol
. 2011 Jul;
20(3):417-23.
PMID: 21783621
A toxic sequel to polyhalogenated aromatic hydrocarbon exposure in humans is the development of porphyria cutanea tarda. In a mouse model (experimental uroporphyria) utilizing an environmentally relevant polychlorinated biphenyl (PCB)...
10.
Lamb J, Hathaway L, Munger M, Raucy J, Franklin M
Drug Metab Dispos
. 2010 Sep;
38(12):2246-51.
PMID: 20861156
Nanosilver particles are present in consumer and health care products. Their effects on human microsomal cytochrome P450 (P450) activities and induction in luciferase reporter-engineered Caco-2 (MDR1.C) and HepG2 (DPX2 and...