Luminita A Stanciu
Overview
Explore the profile of Luminita A Stanciu including associated specialties, affiliations and a list of published articles.
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27
Citations
2109
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Recent Articles
1.
Zhu J, Edwards M, Message S, Stanciu L, Johnston S, Jeffery P
Pharmaceuticals (Basel)
. 2024 Nov;
17(11).
PMID: 39598462
Cilomilast, a phosphodiesterase-4 (PDE4) selective inhibitor, has anti-inflammatory effects in vitro and in vivo and reduces COPD exacerbations. We tested the hypothesis that cilomilast inhibits virus-induced airway epithelial intercellular adhesion...
2.
Zhu J, Mallia P, Footitt J, Qiu Y, Message S, Kebadze T, et al.
J Allergy Clin Immunol
. 2020 Apr;
146(4):840-850.e7.
PMID: 32283204
Background: Respiratory viral infection causes chronic obstructive pulmonary disease (COPD) exacerbations. We previously reported increased bronchial mucosa eosinophil and neutrophil inflammation in patients with COPD experiencing naturally occurring exacerbations. But...
3.
Nikonova A, Khaitov M, Jackson D, Traub S, Trujillo-Torralbo M, Kudlay D, et al.
EBioMedicine
. 2020 Apr;
54:102734.
PMID: 32279057
Background: Macrophages (Mф) can be M1/M2 polarized by Th1/2 signals, respectively. M2-like Mф are thought to be important in asthma pathogenesis, and M1-like in anti-infective immunity, however their roles in...
4.
Feketea G, Bocsan C, Popescu C, Gaman M, Stanciu L, Zdrenghea M
Cells
. 2019 May;
8(5).
PMID: 31071965
There is an imbalance in asthma between classically activated macrophages (M1 cells) and alternatively activated macrophages (M2 cells) in favor of the latter. MicroRNAs (miRNAs) play a critical role in...
5.
Pop R, Popolo A, Trifa A, Stanciu L
Oxid Med Cell Longev
. 2018 Aug;
2018:1603872.
PMID: 30159110
No abstract available.
6.
Zhu J, Message S, Mallia P, Kebadze T, Contoli M, Ward C, et al.
J Allergy Clin Immunol
. 2018 Apr;
143(1):114-125.e4.
PMID: 29698627
Background: The innate immune system senses viral infection through pattern recognition receptors (PRRs), leading to type I interferon production. The role of type I interferon and PPRs in rhinovirus-induced asthma...
7.
Upton N, Jackson D, Nikonova A, Hingley-Wilson S, Khaitov M, Del Rosario A, et al.
PLoS One
. 2017 Sep;
12(8):e0183864.
PMID: 28859129
Rhinovirus infection is associated with the majority of asthma exacerbations. The role of fractalkine in anti-viral (type 1) and pathogenic (type 2) responses to rhinovirus infection in allergic asthma is...
8.
Telcian A, Zdrenghea M, Edwards M, Laza-Stanca V, Mallia P, Johnston S, et al.
Antiviral Res
. 2016 Nov;
137:93-101.
PMID: 27838350
Background: By modulating the antiviral immune response via vitamin D receptor, the active form of vitamin D (1,25-dihydroxyvitamin D, calcitriol) could play a central role in protection against respiratory virus...
9.
Zdrenghea M, Makrinioti H, Bagacean C, Bush A, Johnston S, Stanciu L
Rev Med Virol
. 2016 Oct;
27(1).
PMID: 27714929
Vitamin D, in addition to its classical functions in bone homeostasis, has a modulatory and regulatory role in multiple processes, including host defense, inflammation, immunity, and epithelial repair. Patients with...
10.
Zdrenghea M, Makrinioti H, Muresan A, Johnston S, Stanciu L
Rev Med Virol
. 2014 Nov;
25(1):33-49.
PMID: 25430775
Activation through different signaling pathways results in two functionally different types of macrophages, the pro-inflammatory (M1) and the anti-inflammatory (M2). The polarization of macrophages toward the pro-inflammatory M1 phenotype is...