Michael Place
Overview
Explore the profile of Michael Place including associated specialties, affiliations and a list of published articles.
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35
Citations
1324
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Recent Articles
1.
Rojas J, Hose J, Dutcher H, Place M, Wolters J, Hittinger C, et al.
Cell Genom
. 2024 Sep;
4(10):100656.
PMID: 39317188
Although implicated as deleterious in many organisms, aneuploidy can underlie rapid phenotypic evolution. However, aneuploidy will be maintained only if the benefit outweighs the cost, which remains incompletely understood. To...
2.
Myers K, Place M, Gasch A, Noguera D, Donohue T
Microbiol Resour Announc
. 2024 Jul;
13(9):e0035624.
PMID: 39083691
Multiplex, randomized CRISPR interference sequencing (MuRCiS) allows for the simultaneous identification of multiple gene knockouts that together influence microbial processes. Here, we report on an updated analysis tool called Auto-MuRCiS...
3.
Bacon E, Myers K, Iruegas-Lopez R, Banta A, Place M, Ebersberger I, et al.
bioRxiv
. 2024 Jul;
PMID: 39026751
The Gram-negative pathogen is considered an "urgent threat" to human health due to its propensity to become antibiotic resistant. Understanding the distinct regulatory paradigms used by to mitigate cellular stresses...
4.
Escalante L, Hose J, Howe H, Paulsen N, Place M, Gasch A
bioRxiv
. 2024 Jul;
PMID: 38948718
Premature aging is a hallmark of Down syndrome, caused by trisomy of human chromosome 21, but the reason is unclear and difficult to study in humans. We used an aneuploid...
5.
Rojas J, Hose J, Dutcher H, Place M, Wolters J, Hittinger C, et al.
bioRxiv
. 2024 Apr;
PMID: 38645209
Although implicated as deleterious in many organisms, aneuploidy can underlie rapid phenotypic evolution. However, aneuploidy will only be maintained if the benefit outweighs the cost, which remains incompletely understood. To...
6.
Banta A, Myers K, Ward R, Cuellar R, Place M, Freeh C, et al.
bioRxiv
. 2024 Mar;
PMID: 38496613
Targeted, genome-scale gene perturbation screens using Clustered Regularly Interspaced Short Palindromic Repeats interference (CRISPRi) and activation (CRISPRa) have revolutionized eukaryotic genetics, advancing medical, industrial, and basic research. Although CRISPRi knockdowns...
7.
Bonde N, Wood E, Myers K, Place M, Keck J, Cox M
J Bacteriol
. 2023 Nov;
205(12):e0018423.
PMID: 38019006
DNA damage and subsequent DNA repair processes are mutagenic in nature and an important driver of evolution in prokaryotes, including antibiotic resistance development. Genetic screening approaches, such as transposon sequencing...
8.
Robinson D, Vanacloig-Pedros E, Cai R, Place M, Hose J, Gasch A
bioRxiv
. 2023 Jul;
PMID: 37503218
Variation in gene copy number can alter gene expression and influence downstream phenotypes; thus copy-number variation (CNV) provides a route for rapid evolution if the benefits outweigh the cost. We...
9.
Robinson D, Vanacloig-Pedros E, Cai R, Place M, Hose J, Gasch A
G3 (Bethesda)
. 2023 Jul;
13(10).
PMID: 37481264
Variation in gene copy number can alter gene expression and influence downstream phenotypes; thus copy-number variation provides a route for rapid evolution if the benefits outweigh the cost. We recently...
10.
Zhang Y, Myers K, Place M, Serate J, Xie D, Pohlmann E, et al.
Microbiol Resour Announc
. 2022 Aug;
11(9):e0056422.
PMID: 35993778
The transcriptomes of Zymomonas mobilis 2032 were captured during the fermentation of ammonia fiber expansion (AFEX)-pretreated corn stover and switchgrass hydrolysates containing different concentrations of glucose and xylose. RNA samples...