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Michael Paul Murphy

Explore the profile of Michael Paul Murphy including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 271
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Recent Articles
1.
Womack T, Vollert C, Ohia-Nwoko O, Schmitt M, Montazari S, Beckett T, et al.
Front Cell Neurosci . 2022 Feb; 16:769347. PMID: 35197825
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is the most common form of dementia in aged populations. A substantial amount of data demonstrates that chronic neuroinflammation can accelerate...
2.
Niedowicz D, Reeves V, Platt T, Kohler K, Beckett T, Powell D, et al.
Acta Neuropathol Commun . 2014 Jun; 2:64. PMID: 24916066
Mid-life obesity and type 2 diabetes mellitus (T2DM) confer a modest, increased risk for Alzheimer's disease (AD), though the underlying mechanisms are unknown. We have created a novel mouse model...
3.
Cenini G, Dowling A, Beckett T, Barone E, Mancuso C, Murphy M, et al.
Biochim Biophys Acta . 2011 Oct; 1822(2):130-8. PMID: 22009041
Down syndrome (DS) is the most common genetic cause of intellectual disability in children, and the number of adults with DS reaching old age is increasing. By the age of...
4.
Barone E, Cenini G, Di Domenico F, Martin S, Sultana R, Mancuso C, et al.
Pharmacol Res . 2011 Jan; 63(3):172-80. PMID: 21193043
Alzheimer disease (AD) is an age-related neurodegenerative disorder characterized by progressive memory loss, inability to perform the activities of daily living and personality changes. Unfortunately, drugs effective for this disease...
5.
Kukar T, Murphy M, Eriksen J, Sagi S, Weggen S, Smith T, et al.
Nat Med . 2005 Apr; 11(5):545-50. PMID: 15834426
Increased Abeta42 production has been linked to the development of Alzheimer disease. We now identify a number of compounds that raise Abeta42. Among the more potent Abeta42-raising agents identified are...