Cesare Mancuso
Overview
Explore the profile of Cesare Mancuso including associated specialties, affiliations and a list of published articles.
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81
Citations
3180
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Recent Articles
1.
Mancuso C
Antioxidants (Basel)
. 2025 Feb;
14(2).
PMID: 40002374
Heme oxygenase (HO) metabolizes heme into ferrous iron, carbon monoxide (CO), and biliverdin-IXα (BV), the latter being reduced into bilirubin-IXα (BR) by the biliverdin reductase-A (BVR). Heme oxygenase exists as...
2.
Mancuso C
Nutrients
. 2024 Jul;
16(13).
PMID: 38999868
Current evidence suggests a beneficial role of herbal products in free radical-induced diseases. (Burk.) F. H. Chen has long occupied a leading position in traditional Chinese medicine because of the...
3.
Mancuso C
Free Radic Biol Med
. 2023 Jul;
207:133-143.
PMID: 37459935
Biliverdin is one of the three by-products of heme oxygenase (HO) activity, the others being ferrous iron and carbon monoxide. Under physiological conditions, once formed in the cell, BV is...
4.
Mancuso C
Front Pharmacol
. 2023 May;
14:1156333.
PMID: 37153762
Heme oxygenase (HO-2) is an enzyme mainly involved in the physiologic turnover of heme and intracellular gas sensing, and it is very abundant in the brain, testes, kidneys and vessels....
5.
de Waure C, Bertola C, Baccarini G, Chiavarini M, Mancuso C
Pharmaceutics
. 2023 Apr;
15(4).
PMID: 37111761
Although the anticancer role of curcumin has been extensively addressed in preclinical research, only a few studies were carried out in humans, with conflicting results. The aim of this systematic...
6.
Mancuso C
Expert Opin Ther Targets
. 2022 Mar;
26(4):361-374.
PMID: 35285395
Introduction: The heme oxygenase/biliverdin reductase (HO/BVR) system is involved in heme metabolism. The inducible isoform of HO (HO-1) and BVR both exert cytoprotective effects by enhancing cell stress response. In...
7.
Mancuso C
Free Radic Biol Med
. 2021 Jul;
172:521-529.
PMID: 34224815
Biliverdin reductase-A (BVR) catalyzes the reduction of heme-derived biliverdin into bilirubin, this latter being a powerful endogenous free radical scavenger. Furthermore, BVR is also endowed with both serine/threonine/tyrosine kinase and...
8.
Mhillaj E, Papi M, Paciello F, Silvestrini A, Rolesi R, Palmieri V, et al.
Front Cell Dev Biol
. 2020 Nov;
8:561179.
PMID: 33134292
The formation and aggregation of amyloid-β-peptide (Aβ) into soluble and insoluble species represent the pathological hallmarks of Alzheimer's disease (AD). Over the last few years, however, soluble Aβ (sAβ) prevailed...
9.
10.
Mhillaj E, Cuomo V, Trabace L, Mancuso C
Front Pharmacol
. 2019 Nov;
10:1298.
PMID: 31780933
Over the last few years, several preclinical studies have shown that some herbal products, such as ferulic acid, , and resveratrol, exert neuroprotective effects through the modulation of the heme...