Michael P Philpott
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Explore the profile of Michael P Philpott including associated specialties, affiliations and a list of published articles.
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45
Citations
1326
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Recent Articles
11.
Le Fang , Trigiante G, Crespo-Otero R, Philpott M, Jones C, Watkinson M
Org Biomol Chem
. 2019 Oct;
17(47):10013-10019.
PMID: 31621740
Zn2+ is involved in a number of biological processes and its wide-ranging roles at the subcellular level, especially in specific organelles, have not yet been fully established due to a...
12.
Le Fang , Trigiante G, Kousseff C, Crespo-Otero R, Philpott M, Watkinson M
Chem Commun (Camb)
. 2018 Aug;
54(69):9619-9622.
PMID: 30095141
A cancer cell-targeting fluorescent sensor has been developed to image mobile Zn2+ by introducing a biotin group. It shows a highly selective response to Zn2+in vitro, no toxicity in cellulo...
13.
Bladen J, Wang J, Sangaralingam A, Moosajee M, Fitchett C, Chelala C, et al.
Sci Rep
. 2018 May;
8(1):7531.
PMID: 29760516
Sebaceous gland carcinoma (SGC) is a rare, but life-threatening condition with a predilection for the periocular region. Eyelid SGC can be broadly categorised into two subtypes, namely either nodular or...
14.
Philpott M
Exp Dermatol
. 2018 Apr;
27(5):571-577.
PMID: 29693730
Terence Kealey first pioneered the isolation and organ maintenance of human eccrine and sebaceous glands in the early to mid-1980. This led to subsequent methods describing the isolation and culture...
15.
Kenny F, Drymoussi Z, Delaine-Smith R, Kao A, Laly A, Knight M, et al.
J Cell Sci
. 2018 Apr;
131(10).
PMID: 29669739
Tissue biomechanics regulate a wide range of cellular functions, but the influences on epidermal homeostasis and repair remain unclear. Here, we examined the role of extracellular matrix stiffness on human...
16.
Bladen J, Moosajee M, Tracey-White D, Beaconsfield M, OToole E, Philpott M
Graefes Arch Clin Exp Ophthalmol
. 2018 Feb;
256(4):853-860.
PMID: 29423837
Purpose: Sebaceous carcinoma (SC) is a clinical masquerader of benign conditions resulting in significant eye morbidity, sometimes leading to extensive surgical treatment including exenteration, and even mortality. Little is known...
17.
Caton P, Evans E, Philpott M, Hannen R
Curr Opin Pharmacol
. 2017 Oct;
37:59-64.
PMID: 28985599
Prevalence of obesity and related complications such as type 2 diabetes (T2D) has increased dramatically in recent decades. Metabolic complications of obesity arise in part due to subcutaneous adipose tissue...
18.
Pantazi E, Gemenetzidis E, Teh M, Reddy S, Warnes G, Evagora C, et al.
J Invest Dermatol
. 2017 Mar;
137(8):1719-1730.
PMID: 28300597
Uncontrolled hedgehog (HH)/glioma-associated oncogene (GLI) and WNT/β-catenin signaling are important events in the genesis of many cancers including skin cancer and are often implicated in tumor progression, invasion, and metastasis....
19.
Heilmann-Heimbach S, Herold C, Hochfeld L, Hillmer A, Nyholt D, Hecker J, et al.
Nat Commun
. 2017 Mar;
8:14694.
PMID: 28272467
Male-pattern baldness (MPB) is a common and highly heritable trait characterized by androgen-dependent, progressive hair loss from the scalp. Here, we carry out the largest GWAS meta-analysis of MPB to...
20.
Chew E, Tan J, Bahta A, Ho B, Liu X, Lim T, et al.
J Invest Dermatol
. 2016 Apr;
136(8):1559-1567.
PMID: 27060448
Androgenetic alopecia (AGA) is a common heritable and androgen-dependent hair loss condition in men. Twelve genetic risk loci are known to date, but it is unclear which genes at these...