Michael P Morran
Overview
Explore the profile of Michael P Morran including associated specialties, affiliations and a list of published articles.
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14
Citations
384
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Recent Articles
1.
Kalb R, Nyabuto G, Morran M, Maity S, Justinger J, Nestor-Kalinoski A, et al.
Int J Mol Sci
. 2024 Oct;
25(20).
PMID: 39457021
Glioblastomas (aka Glioblastoma multiformes (GBMs)) are the most deadly of the adult brain tumors. Even with aggressive treatment, the prognosis is extremely poor. The large GTPase Guanylate-Binding Protein-1 (GBP-1) contributes...
2.
Morgan E, Morran M, Horen N, Weaver D, Nestor-Kalinoski A
Physiol Genomics
. 2021 Nov;
53(12):534-545.
PMID: 34755572
Increased arterial stiffness is an independent risk factor for hypertension, stroke, and cardiovascular morbidity. Thus, understanding the factors contributing to vascular stiffness is of critical importance. Here, we used a...
3.
Nandedkar-Kulkarni N, Esakov E, Gregg B, Atkinson M, Rogers D, Horner J, et al.
J Immunol
. 2021 Mar;
206(7):1443-1453.
PMID: 33658296
Insulin receptor (IR) expression on the T cell surface can indicate an activated state; however, the IR is also chemotactic, enabling T cells with high IR expression to physically move...
4.
Pollard C, Morran M, Nestor-Kalinoski A
Physiol Genomics
. 2020 Sep;
52(11):549-557.
PMID: 32991251
The novel coronavirus SARS-CoV-2 was identified as the causative agent for a series of atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019. The disease...
5.
Gordon D, Neifer K, Hamoud A, Hawk C, Nestor-Kalinoski A, Miruzzi S, et al.
J Biol Chem
. 2020 May;
295(29):9804-9822.
PMID: 32404366
Activation of lipid-burning pathways in the fat-storing white adipose tissue (WAT) is a promising strategy to improve metabolic health and reduce obesity, insulin resistance, and type II diabetes. For unknown...
6.
Nandedkar-Kulkarni N, Vartak A, Sucheck S, Wall K, Quinn A, Morran M, et al.
Bioconjug Chem
. 2019 Jul;
30(7):2049-2059.
PMID: 31274300
Type 1 diabetes (T1D) is an autoimmune disorder characterized by autoimmune cell mediated destruction of pancreatic beta cells. Pancreatic beta cells are the only source of insulin in the body....
7.
Acevedo-Calado M, Pietropaolo S, Morran M, Schnell S, Vonberg A, Verge C, et al.
Diabetes
. 2019 Jun;
68(9):1819-1829.
PMID: 31167877
We identified autoantibodies (AAb) reacting with a variant IA-2 molecule (IA-2var) that has three amino acid substitutions (Cys, Gly, and Pro) within the full-length molecule. We examined IA-2var AAb in...
8.
Morran M, Al-Dieri A, Nestor-Kalinoski A, Jordan R, Gupta N, McInerney M
J Biol Methods
. 2018 Jun;
5(1).
PMID: 29862308
The insulin receptor (IR) is a transmembrane receptor which recognizes and binds the hormone insulin. We describe two models that were devised to explore the role of IR over-expression on...
9.
Acevedo-Calado M, James E, Morran M, Pietropaolo S, OuYang Q, Arribas-Layton D, et al.
Diabetes Care
. 2017 Feb;
40(4):561-568.
PMID: 28174261
Objective: The characterization of diverse subtypes of diabetes is a dynamic field of clinical research and an active area of discussion. The objective of this study was to identify new...
10.
Morran M, Vonberg A, Khadra A, Pietropaolo M
Mol Aspects Med
. 2015 Jan;
42:42-60.
PMID: 25579746
Type 1 diabetes mellitus (T1DM) is an autoimmune disease arising through a complex interaction of both genetic and immunologic factors. Similar to the majority of autoimmune diseases, T1DM usually has...