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Michael P McCarthy

Explore the profile of Michael P McCarthy including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 522
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Recent Articles
1.
Peretti A, Scorpio D, Kong W, Pang Y, McCarthy M, Ren K, et al.
Vaccine . 2023 Feb; 41(10):1735-1742. PMID: 36764908
In 2019, there were about 100,000 kidney transplants globally, with more than a quarter of them performed in the United States. Unfortunately, some engrafted organs are lost to polyomavirus-associated nephropathy...
2.
Maynard S, Marshall J, MacGill R, Yu L, Cann J, Cheng L, et al.
BMC Cancer . 2019 Jun; 19(1):540. PMID: 31170937
Background: Despite considerable efforts at developing therapeutic vaccines for cancer, clinical translation of preclinical successes has been challenging, largely due to the difficulty of inducing strong and sustained cytotoxic T...
3.
Jack Borrok M, DiGiandomenico A, Beyaz N, Marchetti G, Barnes A, Lekstrom K, et al.
JCI Insight . 2018 Jun; 3(12). PMID: 29925682
IgG antibodies are abundantly present in the vasculature but to a much lesser extent in mucosal tissues. This contrasts with antibodies of the IgA and IgM isotype that are present...
4.
Gregg K, Harberts E, Gardner F, Pelletier M, Cayatte C, Yu L, et al.
Vaccine . 2018 Jun; 36(28):4023-4031. PMID: 29861179
Vaccination can significantly reduce worldwide morbidity and mortality to infectious diseases, thereby reducing the health burden as a result of microbial infections. Effective vaccines contain three components: a delivery system,...
5.
Cayatte C, Snell Bennett A, Rajani G, Hostetler L, Maynard S, Lazzaro M, et al.
PLoS One . 2017 Nov; 12(11):e0188708. PMID: 29182682
Respiratory syncytial virus (RSV) is recognized as an important cause of lower and upper respiratory tract infections in older adults, and a successful vaccine would substantially lower morbidity and mortality...
6.
Irizarry Gatell V, Nguyen T, Anderson E, McCarthy M, Hardt J
J Health Care Poor Underserved . 2017 Nov; 28(4):1409-1422. PMID: 29176104
We explored medical students' desire to practice medicine in a medically under-served area (MUS). We surveyed M1-M4 students at Loyola University Stritch School of Medicine (66% overall response rate). Primary...
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Gregg K, Harberts E, Gardner F, Pelletier M, Cayatte C, Yu L, et al.
mBio . 2017 May; 8(3). PMID: 28487429
Adjuvant properties of bacterial cell wall components like MPLA (monophosphoryl lipid A) are well described and have gained FDA approval for use in vaccines such as Cervarix. MPLA is the...
9.
Lin R, Heeke D, Liu H, Rao E, Marshall J, Chio V, et al.
J Virol Methods . 2017 May; 247:15-21. PMID: 28457783
The goal of most prophylactic vaccines is to elicit robust and effective neutralizing antibodies against the human pathogen target. The titer of neutralizing antibodies to Epstein-Barr Virus (EBV) is a...
10.
Iyer V, Cayatte C, Marshall J, Sun J, Schneider-Ohrum K, Maynard S, et al.
J Pharm Sci . 2017 Mar; 106(6):1490-1498. PMID: 28259764
To generate potent vaccine responses, subunit protein antigens typically require coformulation with an adjuvant. Oil-in-water emulsions are among the most widely investigated adjuvants, based on their demonstrated ability to elicit...