Michael Obrecht
Overview
Explore the profile of Michael Obrecht including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
6
Citations
48
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Obrecht M, Zurbruegg S, Accart N, Lambert C, Doelemeyer A, Ledermann B, et al.
Front Pharmacol
. 2023 Jul;
14:1177421.
PMID: 37448960
The 3Rs principles-reduction, refinement, replacement-are at the core of preclinical research within drug discovery, which still relies to a great extent on the availability of models of disease in animals....
2.
Saponara E, Penno C, Orsini V, Wang Z, Fischer A, Aebi A, et al.
Am J Pathol
. 2022 Nov;
193(2):161-181.
PMID: 36410420
The roof plate-specific spondin-leucine-rich repeat-containing G-protein coupled receptor 4/5 (LGR4/5)-zinc and ring finger 3 (ZNRF3)/ring finger protein 43 (RNF43) module is a master regulator of hepatic Wnt/β-catenin signaling and metabolic...
3.
Accart N, Dawson J, Obrecht M, Lambert C, Flueckiger M, Kreider J, et al.
Sci Rep
. 2022 Jan;
12(1):157.
PMID: 34997110
The objective of this work was to assess the consequences of repeated intra-articular injection of monosodium urate (MSU) crystals with inflammasome priming by lipopolysaccharide (LPS) in order to simulate recurrent...
4.
Morozzi G, Rothen J, Toussaint G, De Lange K, Westritschnig K, Doelemeyer A, et al.
iScience
. 2021 Dec;
24(12):103434.
PMID: 34877494
Inflammatory responses are crucial for regeneration following peripheral nerve injury (PNI). PNI triggers inflammatory responses at the site of injury. The DNA-sensing receptor cyclic GMP-AMP synthase (cGAS) and its downstream...
5.
Giorgetti E, Panesar M, Zhang Y, Joller S, Ronco M, Obrecht M, et al.
Cell Rep
. 2019 Nov;
29(6):1539-1554.e7.
PMID: 31693894
Age-related loss of skeletal muscle innervation by motor neurons leads to impaired neuromuscular function and is a well-established clinical phenomenon. However, the underlying pathogenesis remains unclear. Studying mice, we find...
6.
Giorgetti E, Obrecht M, Ronco M, Panesar M, Lambert C, Accart N, et al.
Sci Rep
. 2019 Sep;
9(1):13508.
PMID: 31534149
Assessment of myelin integrity in peripheral nerve injuries and pathologies has largely been limited to post-mortem analysis owing to the difficulty in obtaining biopsies without affecting nerve function. This is...