Michael McGeachie
Overview
Explore the profile of Michael McGeachie including associated specialties, affiliations and a list of published articles.
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29
Citations
334
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Recent Articles
1.
Mendez K, Kachroo P, Prince N, Huang M, Cote M, Chu S, et al.
Am J Respir Crit Care Med
. 2025 Feb;
PMID: 39965055
Rationale: Pediatric asthma is heterogeneous, with varied clinical presentations and treatment responses. Metabolomic profiling may uncover shared and unique biological mechanisms across clinical traits that characterize pediatric asthma. Objectives: To...
2.
Mendez K, Reinke S, Kelly R, Chen Q, Su M, McGeachie M, et al.
Nat Commun
. 2025 Feb;
16(1):1700.
PMID: 39962039
The promise of integrating Electronic Medical Records (EMR) and genetic data for precision medicine has largely fallen short due to its omission of environmental context over time. Post-genomic data can...
3.
Sharma R, Mendez K, Begum S, Chu S, Prince N, Hecker J, et al.
EBioMedicine
. 2024 Dec;
112:105534.
PMID: 39740296
Background: There are important inter-relationships between miRNAs and metabolites: alterations in miRNA expression can be induced by various metabolic stimuli, and miRNAs play a regulatory role in numerous cellular processes,...
4.
Mirzakhani H, Wang A, Sharma R, Sun M, Panganiban R, Lu Q, et al.
J Allergy Clin Immunol
. 2024 Dec;
PMID: 39724972
Background: MicroRNAs (miRNAs) are involved in the biological regulation of asthma and allergies. Objective: We sought to investigate the association between cord blood miRNAs and the development of allergic rhinitis...
5.
Carreras-Gallo N, Chen Q, Balague-Dobon L, Aparicio A, Giosan I, Dargham R, et al.
medRxiv
. 2024 Dec;
PMID: 39677461
The lack of accurate, cost-effective, and clinically relevant biomarkers remains a major barrier to incorporating omic data into clinical practice. Previous studies have shown that DNA methylation algorithms have utility...
6.
Kim B, Yang M, Srivastava U, Piparia S, Sharma R, Tiwari A, et al.
Clin Exp Allergy
. 2024 Nov;
55(1):67-74.
PMID: 39489493
Introduction: MicroRNAs (miRNAs) have been linked to allergic diseases but their effects on sensitisation to allergens in individuals with asthma are unknown. We aimed to identify miRNAs associated with house...
7.
Piparia S, Hecker J, Srivastava U, Sharma R, Khare M, Kho A, et al.
Clin Exp Allergy
. 2024 Oct;
55(2):193-195.
PMID: 39357540
No abstract available.
8.
Nopsopon T, Chen Y, Chen Q, Wheelock C, Weiss S, McGeachie M, et al.
ERJ Open Res
. 2024 Aug;
10(4).
PMID: 39104961
Background: There is limited evidence on biomarkers associated with response to the monoclonal antibodies currently approved for asthma treatment. We sought to identify circulatory metabolites associated with response to treatment...
9.
Eicher T, Kelly R, Braisted J, Siddiqui J, Celedon J, Clish C, et al.
medRxiv
. 2024 Jun;
PMID: 38883716
Serum total immunoglobulin E levels (total IgE) capture the state of the immune system in relation to allergic sensitization. High levels are associated with airway obstruction and poor clinical outcomes...
10.
Voorhies K, Mohammed A, Chinthala L, Kong S, Lee I, Kho A, et al.
Genes (Basel)
. 2024 Apr;
15(4).
PMID: 38674355
Inhaled corticosteroids (ICS) are efficacious in the treatment of asthma, which affects more than 300 million people in the world. While genome-wide association studies have identified genes involved in differential...