Michael McCaman
Overview
Explore the profile of Michael McCaman including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
194
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Recent Articles
1.
Braatz J, Elias C, Finny J, Tran H, McCaman M
J Immunol Methods
. 2014 Dec;
417:131-133.
PMID: 25527344
An Enzyme-Linked Immunosorbent Assay (ELISA) has been developed for the quantitation of porcine trypsin as a process residual in cell therapy products based on its capture by either of two...
2.
van den Bos C, Keefe R, Schirmaier C, McCaman M
Adv Biochem Eng Biotechnol
. 2013 Aug;
138:61-97.
PMID: 23934363
: Human primary cells (e.g. adult stem cells) as well as differentiated cells, including those of the immune system, have been found to be therapeutically useful and free of ethical...
3.
Clarke D, Harati D, Martin J, Rowley J, Keller J, McCaman M, et al.
Cytotherapy
. 2012 Aug;
14(9):1032-40.
PMID: 22900960
he concept of particulates, while common to many in the pharmaceutical and blood transfusion disciplines, represents a distinct challenge in the field of cellular therapy. With newly discovered products advancing...
4.
Carmen J, Burger S, McCaman M, Rowley J
Regen Med
. 2011 Dec;
7(1):85-100.
PMID: 22168500
A major challenge to commercializing cell-based therapies is developing scalable manufacturing processes while maintaining the critical quality parameters (identity, potency, purity, safety) of the final live cell product. Process development...
5.
Zheng X, Baker H, Hancock W, Fawaz F, McCaman M, Pungor Jr E
Biotechnol Prog
. 2006 Oct;
22(5):1294-300.
PMID: 17022666
Fetal bovine serum (FBS) is the most widely used growth supplement for cell cultures, primarily because of its high levels of growth stimulatory factors and low levels of growth inhibitory...
6.
Yu T, Traina J, Pungor 2nd E, McCaman M
Anal Biochem
. 2006 Oct;
359(1):54-62.
PMID: 17010928
Standard SDS-PAGE analysis of a pegylated protein was able to confirm an increase in its molecular size after reaction with an activated polyethylene glycol (PEG) but could do little to...
7.
Rosser M, Xia W, Hartsell S, McCaman M, Zhu Y, Wang S, et al.
Protein Expr Purif
. 2005 Mar;
40(2):237-43.
PMID: 15766864
With the recent completion of the human genome sequencing project, scientists now face the daunting challenge of deciphering the function of these newly found genes quickly and efficiently. For biotechnology,...
8.
Murakami P, Havenga M, Fawaz F, Vogels R, Marzio G, Pungor E, et al.
J Virol
. 2004 May;
78(12):6200-8.
PMID: 15163713
The use of the PER.C6 adenovirus packaging cell line in combination with a designated vector plasmid system, whereby the cell line and vector with E1 deleted have no sequence overlap,...
9.
Murakami P, Pungor E, Files J, Do L, van Rijnsoever R, Vogels R, et al.
Hum Gene Ther
. 2002 May;
13(8):909-20.
PMID: 12031124
An undesirable byproduct from recombinant adenoviral vectors is the emergence of replication competent adenovirus (RCA) that result from rare homologous recombination events between the viral E1-containing (permissive) mammalian host cell...