Michael M Seidman
Overview
Explore the profile of Michael M Seidman including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
70
Citations
1929
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pokharel D, Shaik A, Gali H, Ling C, Bellani M, Seidman M
bioRxiv
. 2024 Sep;
PMID: 39257800
Abstract Figure:
2.
Bellani M, Shaik A, Majumdar I, Ling C, Seidman M
DNA Repair (Amst)
. 2024 Aug;
141:103739.
PMID: 39106540
Genomic interstrand crosslinks (ICLs) are formed by reactive species generated during normal cellular metabolism, produced by the microbiome, and employed in cancer chemotherapy. While there are multiple options for replication...
3.
Bellani M, Shaik A, Majumdar I, Ling C, Seidman M
Cells
. 2023 Nov;
12(22).
PMID: 37998342
Duplication of the genome requires the replication apparatus to overcome a variety of impediments, including covalent DNA adducts, the most challenging of which is on the leading template strand. Replisomes...
4.
Bellani M, Huang J, Zhang J, Gali H, Thazhathveetil A, Pokharel D, et al.
DNA Repair (Amst)
. 2023 Jun;
128:103525.
PMID: 37320956
Immunofluorescence imaging is a standard experimental tool for monitoring the response of cellular factors to DNA damage. Visualizing the recruitment of DNA Damage Response (DDR) components requires high affinity antibodies,...
5.
Wang Y, Ferrucci L, Seidman M, Liu Y
STAR Protoc
. 2022 Aug;
3(3):101610.
PMID: 36035793
Telomere dysfunction-induced foci (TIF) can be measured by immunofluorescence, combined with telomere-fluorescent hybridization. We modified this approach by combining the proximity ligation assay (PLA), which detects colocalization of two molecules...
6.
Ellis N, Zhu J, Yagle M, Yang W, Huang J, Kwako A, et al.
Front Genet
. 2021 Dec;
12:753535.
PMID: 34868226
Sumoylation is an important enhancer of responses to DNA replication stress and the SUMO-targeted ubiquitin E3 ligase RNF4 regulates these responses by ubiquitylation of sumoylated DNA damage response factors. The...
7.
James R, Bellani M, Zhang J, Huang J, Shaik A, Pokharel D, et al.
Methods Enzymol
. 2021 Nov;
661:53-75.
PMID: 34776223
Replication forks encounter numerous challenges as they move through eu- and hetero-chromatin during S phase in mammalian cells. These include a variety of impediments to the unwinding of DNA by...
8.
Katsuki Y, Abe M, Park S, Wu W, Yabe H, Yabe M, et al.
Cell Rep
. 2021 Oct;
37(4):109879.
PMID: 34706224
SLX4/FANCP is a key Fanconi anemia (FA) protein and a DNA repair scaffold for incision around a DNA interstrand crosslink (ICL) by its partner XPF nuclease. The tandem UBZ4 ubiquitin-binding...
9.
Zhang J, Bellani M, Huang J, James R, Pokharel D, Gichimu J, et al.
Front Cell Dev Biol
. 2021 Sep;
9:729265.
PMID: 34532320
Replisomes follow a schedule in which replication of DNA in euchromatin is early in S phase while sequences in heterochromatin replicate late. Impediments to DNA replication, referred to as replication...
10.
Zhang J, Huang J, James R, Gichimu J, Paramasivam M, Pokharel D, et al.
J Vis Exp
. 2021 Aug;
(173).
PMID: 34398140
Considerable insight is present into the cellular response to double strand breaks (DSBs), induced by nucleases, radiation, and other DNA breakers. In part, this reflects the availability of methods for...