Michael Lee
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Explore the profile of Michael Lee including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Ng F, Verma R, Sani L, Irwanto A, Lee M, Wee A, et al.
Pharmacogenomics J
. 2025 Mar;
25(1-2):7.
PMID: 40074758
In view of the limited data related to preemptive pharmacogenomics (PGx) testing in the primary care setting, we designed a study to assess the feasibility of implementing preemptive PGx services...
2.
Lee J, Barnett S, Roberts K, Ashwin H, Milross L, Cho J, et al.
Nat Commun
. 2025 Mar;
16(1):1979.
PMID: 40064844
The most common cause of death due to COVID-19 remains respiratory failure. Yet, our understanding of the precise cellular and molecular changes underlying lung alveolar damage is limited. Here, we...
3.
Kokoris M, McRuer R, Nabavi M, Jacobs A, Prindle M, Cech C, et al.
bioRxiv
. 2025 Mar;
PMID: 40060512
Remarkable advances in high-throughput sequencing have enabled major biological discoveries and clinical applications, but achieving wider distribution and use depends critically on further improvements in scale and cost reduction. Nanopore...
4.
Seidel H, Benson D, Litvak A, Lee M, El Dafrawy M
N Am Spine Soc J
. 2025 Mar;
21:100577.
PMID: 40026323
Background: HIV has been associated with cervical myelopathy, but it is unclear if HIV leads to earlier presentation of DCM and need for decompression surgery. Furthermore, long-term rates of postoperative...
5.
De Cruz R, Nguyen R, Chen P, Kerob D, Gebauer K, Willems A, et al.
Australas J Dermatol
. 2025 Feb;
PMID: 40019045
Acne vulgaris is a globally prevalent dermatological disease, with its severity ranging from mild to severe. While moderate to severe acne often requires topical or systemic pharmaceutical therapy, mild to...
6.
Didloff J, Boukes G, Nyambe M, Beukes D, Lerata M, Vilane V, et al.
Antibiotics (Basel)
. 2025 Feb;
14(2).
PMID: 40001422
Background/objectives: Tuberculosis remains a major public health crisis, and it is imperative to search for new antimycobacterial drugs. Natural products, including medicinal macrofungi, have been used as sources for the...
7.
Oestreich M, Merdivan E, Lee M, Schultze J, Piraud M, Becker M
J Cheminform
. 2025 Feb;
17(1):23.
PMID: 40001177
With the cost/yield-ratio of drug development becoming increasingly unfavourable, recent work has explored machine learning to accelerate early stages of the development process. Given the current success of deep generative...
8.
Kang M, Ang T, Devine S, Sherva R, Mukherjee S, Trittschuh E, et al.
medRxiv
. 2025 Feb;
PMID: 39990565
Background: Genome-wide association studies (GWAS) have identified over 1,000 blood pressure (BP) loci and over 80 loci for Alzheimer's disease (AD). Considering BP is an AD risk factor, identifying pleiotropy...
9.
Tadros R, Zheng S, Grace C, Jorda P, Francis C, West D, et al.
Nat Genet
. 2025 Feb;
57(3):530-538.
PMID: 39966646
Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality with both monogenic and polygenic components. Here, we report results from a large genome-wide association study and multitrait analysis...
10.
Mancini F, Mahajan P, Guttesen A, Onysk J, Scholtes I, Shenker N, et al.
Brain
. 2025 Jan;
PMID: 39786367
Chronic pain and fatigue in musculoskeletal disease contribute significantly to disability, and recent studies suggest an association with reduced motivation and excessive fear avoidance. In this behavioural neuroimaging study, we...