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Michael Lean

Explore the profile of Michael Lean including associated specialties, affiliations and a list of published articles. Areas
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Citations 124
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Recent Articles
1.
Ricketts H, Sharma V, Steffensen F, Mackay E, MacDonald G, Buchan D, et al.
J Asthma Allergy . 2024 Sep; 17:911-928. PMID: 39346093
Introduction: Management of difficult-to-treat asthma is particularly challenging in people with elevated body mass index (BMI). Our randomised controlled trial of pulmonary rehabilitation (PR) showed improved outcomes at 8 weeks....
2.
Papamargaritis D, Al-Najim W, Lim J, Crane J, Bodicoat D, Barber S, et al.
Lancet Reg Health Eur . 2024 May; 39:100853. PMID: 38803628
Background: An effective prescribing pathway for liraglutide 3 mg, an approved obesity pharmacotherapy, may improve treatment access. This trial compared a targeted prescribing pathway for liraglutide 3 mg with multiple...
3.
Chimoriya R, Mitlehner K, Khoo C, Osuagwu U, Thomson R, Si L, et al.
J Diabetes Res . 2024 Feb; 2024:2350551. PMID: 38361965
Background: The Diabetes Remission Clinical Trial (DiRECT) study demonstrated that an intensive and structured weight management program in UK primary care resulted in high rates of diabetes remission in adults...
4.
Chimoriya R, MacMillan F, Lean M, Simmons D, Piya M
Diabet Med . 2024 Feb; 41(6):e15301. PMID: 38311881
Background: The UK Diabetes Remission Clinical Trial (DiRECT) study was replicated in an Australian primary care setting. This qualitative study aimed to explore and understand the perceptions and experiences of...
5.
Rothberg A, Lean M, Laferrere B
Diabetologia . 2024 Jan; 67(4):602-610. PMID: 38189935
The concept of type 2 diabetes remission is evolving rapidly, and gaining wide public and professional interest, following demonstration that with substantial intentional weight loss almost nine in ten people...
6.
Goudswaard L, Smith M, Hughes D, Taylor R, Lean M, Sattar N, et al.
Sci Rep . 2023 Nov; 13(1):21077. PMID: 38030643
Thousands of proteins circulate in the bloodstream; identifying those which associate with weight and intervention-induced weight loss may help explain mechanisms of diseases associated with adiposity. We aimed to identify...
7.
Luli M, Yeo G, Farrell E, Ogden J, Parretti H, Frew E, et al.
EClinicalMedicine . 2023 Apr; 58:101962. PMID: 37090435
Unlike various countries and organisations, including the World Health Organisation and the European Parliament, the United Kingdom does not formally recognise obesity as a disease. This report presents the discussion...
8.
Li D, El-Harasis M, Montgomery J, Richardson T, Kanagasundram A, Carlos Estrada J, et al.
J Cardiovasc Electrophysiol . 2022 May; 33(8):1655-1664. PMID: 35598280
Introduction: To target posterior wall isolation (PWI) in atrial fibrillation (AF) ablation, diffuse ablation theoretically confers a lower risk of conduction recovery compared to box set. We sought to assess...
9.
Dick K, Schneider J, Briggs A, Lecomte P, Regnier S, Lean M
Health Econ Rev . 2021 May; 11(1):16. PMID: 33990897
Background: Mendelian Randomization is a type of instrumental variable (IV) analysis that uses inherited genetic variants as instruments to estimate causal effects attributable to genetic factors. This study aims to...
10.
Williamson K, Nimegeer A, Lean M
Obes Rev . 2020 Feb; 21(4):e12986. PMID: 32017386
Whilst previously rare, some surveys indicate substantial increases in the population with body mass index (BMI) ≥40 kg/m since the 1980s. Clinicians report emerging care challenges for this population, often...