Michael L Neugent
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Explore the profile of Michael L Neugent including associated specialties, affiliations and a list of published articles.
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18
Citations
405
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Recent Articles
1.
Lutz K, Neugent M, Bedi T, De Nisco N, Li Q
Stat Med
. 2025 Jan;
44(3-4):e10291.
PMID: 39853798
Advances in next-generation sequencing technology have enabled the high-throughput profiling of metagenomes and accelerated microbiome studies. Recently, there has been a rise in quantitative studies that aim to decipher the...
2.
Saenz C, Neugent M, De Nisco N
Eur Urol Focus
. 2025 Jan;
10(6):889-892.
PMID: 39827037
After identifying a urinary microbiota, new insights have emerged into how urinary tract infections (UTIs) develop and recur in women. This review explores factors influencing the urinary microbiome, and its...
3.
Lutz K, Jiang S, Neugent M, De Nisco N, Zhan X, Li Q
Front Appl Math Stat
. 2024 Nov;
8.
PMID: 39575140
In the last decade, numerous statistical methods have been developed for analyzing microbiome data generated from high-throughput next-generation sequencing technology. Microbiome data are typically characterized by zero inflation, overdispersion, high...
4.
Neugent M, Hulyalkar N, Ghosh D, Zimmern P, Shulaev V, De Nisco N
bioRxiv
. 2024 Nov;
PMID: 39484483
Recurrent urinary tract infections (rUTIs) are a major clinical challenge in postmenopausal women and their increasing prevalence underscores the need to define interactions between the host and the urinary microbiome...
5.
Sharon B, Arute A, Nguyen A, Tiwari S, Reddy Bonthu S, Hulyalkar N, et al.
mBio
. 2023 Nov;
14(6):e0251523.
PMID: 37962362
Urinary tract infection (UTI) is a global health issue that imposes a substantial burden on healthcare systems. Women are disproportionately affected by UTI, with >60% of women experiencing at least...
6.
Sharon B, Arute A, Nguyen A, Tiwari S, Reddy Bonthu S, Hulyalkar N, et al.
bioRxiv
. 2023 Jun;
PMID: 37293065
Importance: Urinary tract infection (UTI) is a global health issue that imposes substantial burden on healthcare systems. Women are disproportionately affected by UTI with >60% of women experiencing at least...
7.
Neugent M, Hulyalkar N, Kumar A, Xing C, Zimmern P, Shulaev V, et al.
ACS Infect Dis
. 2023 Mar;
9(4):1022-1032.
PMID: 36942838
Glycosaminoglycans (GAGs) are linear, negatively charged polysaccharides composed of repeating disaccharide units of uronic acid and amino sugars. The luminal surface of the bladder epithelium is coated with a GAG...
8.
Neugent M, Hulyalkar N, Kumar A, Xing C, Zimmern P, Shulaev V, et al.
bioRxiv
. 2023 Jan;
PMID: 36711817
Glycosaminoglycans (GAGs) are linear, negatively charged polysaccharides composed of repeating disaccharide units of uronic acid and amino sugars. The luminal surface of the bladder epithelium is coated with a GAG...
9.
Neugent M, Kumar A, Hulyalkar N, Lutz K, Nguyen V, Fuentes J, et al.
Cell Rep Med
. 2022 Oct;
3(10):100753.
PMID: 36182683
Postmenopausal women are severely affected by recurrent urinary tract infection (rUTI). The urogenital microbiome is a key component of the urinary environment. However, changes in the urogenital microbiome underlying rUTI...
10.
Salazar A, Neugent M, De Nisco N, Mysorekar I
Cell Host Microbe
. 2022 Aug;
30(8):1066-1069.
PMID: 35952642
The gut microbiome is a critical modulator of systemic physiology, including infectious disease susceptibility. Although this niche is a reservoir for uropathogenic Escherichia coli, knowledge of its role in urinary...