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Michael L Mathai

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Articles 67
Citations 901
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Recent Articles
1.
Thunuguntla V, Kate Gadanec L, McGrath C, Griggs J, Sinnayah P, Apostolopoulos V, et al.
Nutrients . 2025 Jan; 16(24. PMID: 39770917
Background: Obesity is a risk factor for developing cardiovascular diseases (CVDs) by impairing normal vascular function. Natural products are gaining momentum in the clinical setting due to their high efficacy...
2.
Nayyar D, Yan X, Xu G, Shi M, Garnham A, Mathai M, et al.
Nutrients . 2023 Nov; 15(22). PMID: 38004115
This research aimed to determine the effects of Gynostemma pentaphyllum () on exercise performance, AMP-activated protein kinase (AMPK), and mitochondrial signaling in human muscle. This randomized double-blind placebo control crossover...
3.
Vingrys K, Mathai M, McAinch A, Bassett J, de Courten M, Stojanovska L, et al.
Cancer Med . 2023 Sep; 12(18):19188-19202. PMID: 37702114
Background: Cereal-derived polyphenols have demonstrated protective mechanisms in colorectal cancer (CRC) models; however, confirmation in human studies is lacking. Therefore, this study examined the association between cereal polyphenol intakes and...
4.
Vingrys K, Mathai M, Apostolopoulos V, Bassett J, de Courten M, Stojanovska L, et al.
Sci Rep . 2023 May; 13(1):8556. PMID: 37237174
Cereal foods are consumed globally and are important sources of polyphenols with potential health benefits, yet dietary intakes are unclear. We aimed to calculate the dietary intakes of polyphenols from...
5.
OKeefe L, Vu T, Simcocks A, Jenkin K, Mathai M, McAinch A, et al.
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108770
Diet-induced obesity (DIO) is a contributor to co-morbidities, resulting in alterations in hormones, lipids, and low-grade inflammation, with the cannabinoid type 2 receptor (CB) contributing to the inflammatory response. The...
6.
OKeefe L, Vu T, Simcocks A, Jenkin K, Mathai M, Hryciw D, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36232744
Diet-induced obesity (DIO) reduces fatty acid oxidation in skeletal muscle and decreases circulating levels of adiponectin. Endocannabinoid signaling is overactive in obesity, with some effects abated by antagonism of cannabinoid...
7.
Davidson M, Mayer M, Habib A, Rashidi N, Filippone R, Fraser S, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36232524
Methamphetamine (METH) is a highly addictive drug abused by millions of users worldwide, thus becoming a global health concern with limited management options. The inefficiency of existing treatment methods has...
8.
Ranasinghe R, Mathai M, Zulli A
Heliyon . 2022 Sep; 8(9):e10608. PMID: 36158077
Cisplatin spearheads the anticancer chemotherapeutics in present-day use although acute toxicity is its primary impediment factor. Among a plethora of experimental medications, a drug as effective or surpassing the benefits...
9.
Shi M, Mathai M, Xu G, Su X, McAinch A
PLoS One . 2022 Sep; 17(9):e0270306. PMID: 36112580
Obesity is a leading global health problem contributing to various chronic diseases, including type II diabetes mellitus (T2DM). The aim of this study was to investigate whether blueberries, yoghurt, and...
10.
Panchal S, John O, Mathai M, Brown L
Nutrients . 2022 May; 14(10). PMID: 35631301
Anthocyanins are mainly purple-coloured phenolic compounds of plant origin that as secondary metabolites are important in plant survival. Understanding their health benefits in humans requires sourcing these unstable compounds in...