Michael L Hutton
Overview
Explore the profile of Michael L Hutton including associated specialties, affiliations and a list of published articles.
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41
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3358
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Recent Articles
21.
Caselli R, Reiman E, Locke D, Hutton M, Hentz J, Hoffman-Snyder C, et al.
Arch Neurol
. 2007 Sep;
64(9):1306-11.
PMID: 17846270
Background: Memory declines more rapidly with age in apolipoprotein E (APOE) epsilon4 carriers than in APOE epsilon4 noncarriers, and APOE epsilon4 homozygotes' cognitive performances correlate with stressors. These changes could...
22.
Reiman E, Webster J, Myers A, Hardy J, Dunckley T, Zismann V, et al.
Neuron
. 2007 Jun;
54(5):713-20.
PMID: 17553421
The apolipoprotein E (APOE) epsilon4 allele is the best established genetic risk factor for late-onset Alzheimer's disease (LOAD). We conducted genome-wide surveys of 502,627 single-nucleotide polymorphisms (SNPs) to characterize and...
23.
Dickson D, Rademakers R, Hutton M
Brain Pathol
. 2007 May;
17(1):74-82.
PMID: 17493041
Progressive supranuclear palsy (PSP) is an atypical Parkinsonian disorder associated with progressive axial rigidity, vertical gaze palsy, dysarthria and dysphagia. Neuropathologically, the subthalamic nucleus and brainstem, especially the midbrain tectum...
24.
Amador-Ortiz C, Lin W, Ahmed Z, Personett D, Davies P, Duara R, et al.
Ann Neurol
. 2007 May;
61(5):435-45.
PMID: 17469117
Objective: This study aimed to determine the frequency of frontotemporal lobar degeneration with ubiquitinated inclusions (FTLD-U) in the setting of hippocampal sclerosis (HpScl) and Alzheimer's disease (AD) using immunohistochemistry for...
25.
Roder H, Hutton M
Expert Opin Ther Targets
. 2007 Mar;
11(4):435-42.
PMID: 17373874
Interest in the biology of the microtubule-associated protein tau, not only as a pathologic marker, but as a therapeutic target has surged considerably over the last few years. This is...
26.
Whitwell J, Jack Jr C, Baker M, Rademakers R, Adamson J, Boeve B, et al.
Arch Neurol
. 2007 Mar;
64(3):371-6.
PMID: 17353379
Background: Mutations in the progranulin gene (PGRN) have recently been identified as a cause of frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) in some families. Objective: To determine whether there...
27.
Ahmed Z, Mackenzie I, Hutton M, Dickson D
J Neuroinflammation
. 2007 Feb;
4:7.
PMID: 17291356
Progranulin (PGRN) is a pleiotropic protein that has gained the attention of the neuroscience community with recent discoveries of mutations in the gene for PGRN that cause frontotemporal lobar degeneration...
28.
Josephs K, Ahmed Z, Katsuse O, Parisi J, Boeve B, Knopman D, et al.
J Neuropathol Exp Neurol
. 2007 Feb;
66(2):142-51.
PMID: 17278999
Frontotemporal lobar degeneration is heterogeneous; cases with tau- and synuclein-negative, ubiquitin-positive neuronal inclusions are the most common, and some have mutations in the gene for progranulin (PGRN). The purpose of...
29.
Mesulam M, Johnson N, Krefft T, Gass J, Cannon A, Adamson J, et al.
Arch Neurol
. 2007 Jan;
64(1):43-7.
PMID: 17210807
Background: Primary progressive aphasia (PPA) is a language-based dementia characterized by fluent or nonfluent language disorder as its principal feature. Objective: To describe progranulin gene mutations in 2 families with...
30.
Arvanitakis Z, Witte R, Dickson D, Tsuboi Y, Uitti R, Slowinski J, et al.
Parkinsonism Relat Disord
. 2007 Jan;
13(4):230-9.
PMID: 17196872
The objective of this clinical-pathologic study was to identify biomarkers for a pallidopontonigral degeneration (PPND) kindred of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) harboring the N279K tau...