Michael K Showe
Overview
Explore the profile of Michael K Showe including associated specialties, affiliations and a list of published articles.
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23
Citations
915
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Recent Articles
1.
Kossenkov A, Qureshi R, Dawany N, Wickramasinghe J, Liu Q, Majumdar R, et al.
Cancer Res
. 2018 Nov;
79(1):263-273.
PMID: 30487137
Low-dose CT (LDCT) is widely accepted as the preferred method for detecting pulmonary nodules. However, the determination of whether a nodule is benign or malignant involves either repeated scans or...
2.
Fedorov V, Goropashnaya A, Stewart N, Toien O, Chang C, Wang H, et al.
Mol Ecol
. 2014 Oct;
23(22):5524-37.
PMID: 25314618
Hibernation is an energy-saving adaptation that involves a profound suppression of physical activity that can continue for 6-8 months in highly seasonal environments. While immobility and disuse generate muscle loss...
3.
Negorev D, Vladimirova O, Kossenkov A, Demarest R, Showe M, Rauscher 3rd F, et al.
Cancer Res
. 2013 Aug;
73(15):4960-1.
PMID: 23907639
No abstract available.
4.
Showe M, Kossenkov A, Showe L
Oncoimmunology
. 2012 Dec;
1(8):1414-1416.
PMID: 23243612
Attempts to refine and improve outcome predictions using tumor gene expression have been recently reported. We show that peripheral blood mononuclear cell (PBMC)-associated gene signatures can predict outcome in non-small...
5.
Peripheral immune cell gene expression predicts survival of patients with non-small cell lung cancer
Kossenkov A, Dawany N, Evans T, Kucharczuk J, Albelda S, Showe L, et al.
PLoS One
. 2012 Apr;
7(3):e34392.
PMID: 22479623
Prediction of cancer recurrence in patients with non-small cell lung cancer (NSCLC) currently relies on the assessment of clinical characteristics including age, tumor stage, and smoking history. A better prediction...
6.
Duttagupta R, DiRienzo S, Jiang R, Bowers J, Gollub J, Kao J, et al.
PLoS One
. 2012 Feb;
7(2):e31241.
PMID: 22359580
Inflammatory Bowel Disease--comprised of Crohn's Disease and Ulcerative Colitis (UC)--is a complex, multi-factorial inflammatory disorder of the gastrointestinal tract. In this study we have explored the utility of naturally occurring...
7.
Fedorov V, Goropashnaya A, Toien O, Stewart N, Chang C, Wang H, et al.
Funct Integr Genomics
. 2012 Feb;
12(2):357-65.
PMID: 22351243
Physical inactivity reduces mechanical load on the skeleton, which leads to losses of bone mass and strength in non-hibernating mammalian species. Although bears are largely inactive during hibernation, they show...
8.
Kossenkov A, Vachani A, Chang C, Nichols C, Billouin S, Horng W, et al.
Clin Cancer Res
. 2011 Aug;
17(18):5867-77.
PMID: 21807633
Purpose: To characterize the interactions of non-small cell lung cancer (NSCLC) tumors with the immune system at the level of mRNA and microRNA (miRNA) expression and to define expression signatures...
9.
Fedorov V, Goropashnaya A, Toien O, Stewart N, Chang C, Wang H, et al.
BMC Genomics
. 2011 Apr;
12:171.
PMID: 21453527
Background: Hibernation is an adaptive strategy to survive in highly seasonal or unpredictable environments. The molecular and genetic basis of hibernation physiology in mammals has only recently been studied using...
10.
Negorev D, Vladimirova O, Kossenkov A, Nikonova E, Demarest R, Capobianco A, et al.
Cancer Res
. 2010 Dec;
70(23):9991-10001.
PMID: 21118961
Identifying the functions of proteins, which associate with specific subnuclear structures, is critical to understanding eukaryotic nuclear dynamics. Sp100 is a prototypical protein of ND10/PML nuclear bodies, which colocalizes with...