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Michael K Johnson

Explore the profile of Michael K Johnson including associated specialties, affiliations and a list of published articles. Areas
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Articles 96
Citations 3142
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Recent Articles
1.
Vansuch G, Wu C, Haja D, Blair S, Chica B, Johnson M, et al.
Chem Sci . 2021 Jun; 11(32):8572-8581. PMID: 34123117
Metal-ligand cooperativity is an essential feature of bioinorganic catalysis. The design principles of such cooperativity in metalloenzymes are underexplored, but are critical to understand for developing efficient catalysts designed with...
2.
Roret T, Zhang B, Moseler A, Dhalleine T, Gao X, Couturier J, et al.
Antioxidants (Basel) . 2021 Jun; 10(5). PMID: 34069657
Glutaredoxins (GRXs) are thioredoxin superfamily members exhibiting thiol-disulfide oxidoreductase activity and/or iron-sulfur (Fe-S) cluster binding capacities. These properties are determined by specific structural factors. In this study, we examined the...
3.
Azam T, Przybyla-Toscano J, Vignols F, Couturier J, Rouhier N, Johnson M
Int J Mol Sci . 2020 Dec; 21(23). PMID: 33287436
Iron-sulfur (Fe-S) proteins are crucial for many cellular functions, particularly those involving electron transfer and metabolic reactions. An essential monothiol glutaredoxin GRXS15 plays a key role in the maturation of...
4.
Azam T, Przybyla-Toscano J, Vignols F, Couturier J, Rouhier N, Johnson M
J Biol Chem . 2020 Oct; 295(52):18367-18378. PMID: 33122194
Numerous iron-sulfur (Fe-S) proteins with diverse functions are present in the matrix and respiratory chain complexes of mitochondria. Although [4Fe-4S] clusters are the most common type of Fe-S cluster in...
5.
Wang Y, Xie Y, Wei P, Blair S, Cui D, Johnson M, et al.
J Am Chem Soc . 2020 Sep; 142(41):17301-17305. PMID: 32985175
Reaction of the lithium dithiolene radical with the imidazolium salt [{(Me)CN(-Pr)}CH][Cl] (in a 1:1 molar ratio) gives the first stable naked anionic dithiolene radical , which, when coupled with hexasulfide,...
6.
Roland M, Przybyla-Toscano J, Vignols F, Berger N, Azam T, Christ L, et al.
J Biol Chem . 2020 Jan; 295(6):1727-1742. PMID: 31911438
Proteins incorporating iron-sulfur (Fe-S) co-factors are required for a plethora of metabolic processes. Their maturation depends on three Fe-S cluster assembly machineries in plants, located in the cytosol, mitochondria, and...
7.
Wang Y, Xie Y, Wei P, Blair S, Cui D, Johnson M, et al.
Angew Chem Int Ed Engl . 2018 May; 57(26):7865-7868. PMID: 29756257
Whereas low-temperature (-78 °C) reaction of the lithium dithiolene radical 1 with boron bromide gives the dibromoboron dithiolene radical 2 , the parallel reaction of 1 with (C H )...
8.
Benoit S, Holland A, Johnson M, Maier R
Mol Microbiol . 2018 Mar; 108(4):379-396. PMID: 29498770
Helicobacter pylori is anomalous among non nitrogen-fixing bacteria in containing an incomplete NIF system for Fe-S cluster assembly comprising two essential proteins, NifS (cysteine desulfurase) and NifU (scaffold protein). Although...
9.
Gao H, Azam T, Randeniya S, Couturier J, Rouhier N, Johnson M
J Biol Chem . 2018 Feb; 293(12):4422-4433. PMID: 29425096
Dihydroxyacid dehydratase (DHAD) is the third enzyme required for branched-chain amino acid biosynthesis in bacteria, fungi, and plants. DHAD enzymes contain two distinct types of active-site Fe-S clusters. The best...
10.
Vaccaro B, Clarkson S, Holden J, Lee D, Wu C, Poole Ii F, et al.
Nat Commun . 2017 Jul; 8:16110. PMID: 28726794
Iron-sulfur clusters are ubiquitous in biology and function in electron transfer and catalysis. They are assembled from iron and cysteine sulfur on protein scaffolds. Iron is typically stored as iron...