Michael J Podolsky
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Explore the profile of Michael J Podolsky including associated specialties, affiliations and a list of published articles.
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18
Citations
264
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Recent Articles
1.
Podolsky M, Kheyfets B, Pandey M, Beigh A, Yang C, Lizama C, et al.
Nat Commun
. 2024 Feb;
15(1):1531.
PMID: 38378719
Accumulating evidence has implicated impaired extracellular matrix (ECM) clearance as a key factor in fibrotic disease. Despite decades of research elucidating the effectors of ECM clearance, relatively little is understood...
2.
Datta R, Mukherjee D, Podolsky M, Yang C, Alba D, Singh S, et al.
J Biol Chem
. 2024 Jan;
300(2):105631.
PMID: 38199575
Integrins are cell adhesion receptors that dimerize to mediate cell-cell interactions and regulate processes, including proliferation, inflammation, and tissue repair. The role of integrins in regulating insulin signaling is incompletely...
3.
Datta R, Podolsky M, Yang C, Alba D, Singh S, Koliwad S, et al.
bioRxiv
. 2023 Jul;
PMID: 37398282
The role of integrins in regulating insulin signaling is incompletely understood. We have previously shown that binding of the integrin ligand milk fat globule epidermal growth factor like 8 (MFGE8)...
4.
Datta R, Gholampour M, Yang C, Volk R, Lin S, Podolsky M, et al.
Cell Rep
. 2023 Mar;
42(3):112249.
PMID: 36924494
Enterocytes modulate the extent of postprandial lipemia by storing dietary fats in cytoplasmic lipid droplets (cLDs). We have previously shown that the integrin ligand MFGE8 links absorption of dietary fats...
5.
Ivanick N, Shrestha P, Podolsky M, Walavalkar V, Lucas C, Gesthalter Y, et al.
J Thorac Dis
. 2021 Aug;
13(7):4228-4235.
PMID: 34422351
Background: Accurate staging of newly diagnosed or recurrent malignancy is essential for effective treatment. An important first step in staging involves the use of PET/CT to identify areas of FDG...
6.
Datta R, Lizama C, Soltani A, McKleroy W, Podolsky M, Yang C, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(18).
PMID: 33903257
The role of integrins, in particular αv integrins, in regulating insulin resistance is incompletely understood. We have previously shown that the αvβ5 integrin ligand milk fat globule epidermal growth factor...
7.
Atabai K, Yang C, Podolsky M
Am J Respir Cell Mol Biol
. 2020 Jul;
63(4):424-435.
PMID: 32640171
In pathological fibrosis, aberrant tissue remodeling with excess extracellular matrix leads to organ dysfunction and eventual morbidity. Diseases of fibrosis create significant global health and economic burdens and are often...
8.
Podolsky M, Yang C, Lizama Valenzuela C, Datta R, Huang S, Nishimura S, et al.
JCI Insight
. 2020 Apr;
5(10).
PMID: 32315288
Although aging represents the most important epidemiologic risk factor for fibrotic disease, the reasons for this are incompletely understood. Excess collagen deposition in tissues is the sine qua non of...
9.
Datta R, Podolsky M, Atabai K
JCI Insight
. 2018 Oct;
3(19).
PMID: 30282827
At the simplest level, obesity is the manifestation of an imbalance between caloric intake and expenditure; however, the pathophysiological mechanisms that govern the development of obesity and associated complications are...
10.
Podolsky M, Gupta D, Ha A, Ta R, Khalifeh-Soltani A, McKleroy W, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 May;
315(3):L360-L370.
PMID: 29792348
Although extensive work has delineated many of the mechanisms of extracellular matrix (ECM) production, far less is known about pathways that regulate ECM degradation. This is particularly true of cellular...