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Michael J Mauro

Explore the profile of Michael J Mauro including associated specialties, affiliations and a list of published articles. Areas
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Articles 123
Citations 2530
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Recent Articles
1.
Atallah E, Mauro M, Sasaki K, Levy M, Koller P, Yang D, et al.
Future Oncol . 2024 Oct; 20(38):3065-3075. PMID: 39387441
Up to 40% of newly diagnosed patients with chronic myeloid leukemia in chronic phase (CML-CP) discontinue treatment by 5 years, primarily due to resistance or intolerance. Rates of resistance to...
2.
Kockerols C, Valk P, Dulucq S, Nicolini F, Mahon F, Atallah E, et al.
Am J Hematol . 2024 May; 99(8):1632-1635. PMID: 38769689
No abstract available.
3.
Cortes J, Sasaki K, Kim D, Hughes T, Etienne G, Mauro M, et al.
Leukemia . 2024 May; 38(7):1522-1533. PMID: 38755421
Asciminib targets the BCR::ABL1 myristoyl pocket, maintaining activity against BCR::ABL1, which is resistant to most approved adenosine triphosphate-competitive tyrosine kinase inhibitors. We report updated phase I results (NCT02081378) assessing safety/tolerability...
4.
Sweet K, Cortes J, Apperley J, Mann M, Mauro M, Oehler V, et al.
Clin Cancer Res . 2024 Jan; 30(1):237-238. PMID: 38178776
No abstract available.
5.
Winn A, Atallah E, Cortes J, Deininger M, Kota V, Larson R, et al.
JAMA Netw Open . 2023 Dec; 6(12):e2347950. PMID: 38109114
Importance: Patients with chronic myeloid leukemia (CML) who have a sustained deep molecular response using tyrosine kinase inhibitors (TKIs) can safely attempt to stop their use. As these medications are...
6.
Hijiya N, Mauro M
Cancer Manag Res . 2023 Aug; 15:873-891. PMID: 37641687
Tyrosine kinase inhibitors (TKIs) have significantly changed the treatment of chronic myeloid leukemia (CML) and improved outcomes for patients with CML in chronic phase (CML-CP) and accelerated phase (AP). Now...
7.
Cortes J, Rea D, Mauro M, Tran D, Wang P, Jadhav K, et al.
J Med Econ . 2023 Jul; 26(1):915-923. PMID: 37431294
Objectives: To assess and compare health care resource utilization (HCRU) rates of asciminib and bosutinib at the Week 24, Week 48, and Week 96 cutoffs among 3 L + patients...
8.
Shah N, Garcia-Gutierrez V, Jimenez-Velasco A, Larson S, Saussele S, Rea D, et al.
Br J Haematol . 2023 May; 202(5):942-952. PMID: 37246588
Patients with chronic myeloid leukaemia in chronic phase (CML-CP) who have a sustained deep molecular response (DMR) are eligible to discontinue treatment and attempt treatment-free remission (TFR). In the DASFREE...
9.
Rea D, Boquimpani C, Mauro M, Minami Y, Allepuz A, Maheshwari V, et al.
Leukemia . 2023 Apr; 37(5):1060-1067. PMID: 37069326
In ASCEMBL, an open-label, randomized Phase 3 study, asciminib demonstrated superior efficacy and better safety profile compared with bosutinib in patients with chronic myeloid leukemia in chronic phase (CML-CP) previously...
10.
Mauro M, Hughes T, Kim D, Rea D, Cortes J, Hochhaus A, et al.
Leukemia . 2023 Mar; 37(5):1048-1059. PMID: 36949155
Asciminib is approved for patients with Philadelphia chromosome-positive chronic-phase chronic myeloid leukemia (CML-CP) who received ≥2 prior tyrosine kinase inhibitors or have the T315I mutation. We report updated results of...