Michael J Kulik
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Explore the profile of Michael J Kulik including associated specialties, affiliations and a list of published articles.
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8
Citations
440
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Recent Articles
1.
Lyu X, Rowley M, Kulik M, Dalton S, Corces V
Nat Commun
. 2023 Oct;
14(1):6314.
PMID: 37813869
Transcription reprogramming during cell differentiation involves targeting enhancers to genes responsible for establishment of cell fates. To understand the contribution of CTCF-mediated chromatin organization to cell lineage commitment, we analyzed...
2.
Dookwah M, Wagner S, Ishihara M, Yu S, Ulrichs H, Kulik M, et al.
Hum Mol Genet
. 2023 Sep;
32(24):3323-3341.
PMID: 37676252
GM3 Synthase Deficiency (GM3SD) is a neurodevelopmental disorder resulting from pathogenic variants in the ST3GAL5 gene, which encodes GM3 synthase, a glycosphingolipid (GSL)-specific sialyltransferase. This enzyme adds a sialic acid...
3.
Dileep V, Wilson K, Marchal C, Lyu X, Zhao P, Li B, et al.
Stem Cell Reports
. 2019 Jun;
13(1):193-206.
PMID: 31231024
The temporal order of DNA replication is regulated during development and is highly correlated with gene expression, histone modifications and 3D genome architecture. We tracked changes in replication timing, gene...
4.
Rivera-Mulia J, Buckley Q, Sasaki T, Zimmerman J, Didier R, Nazor K, et al.
Genome Res
. 2015 Jun;
25(8):1091-103.
PMID: 26055160
Duplication of the genome in mammalian cells occurs in a defined temporal order referred to as its replication-timing (RT) program. RT changes dynamically during development, regulated in units of 400-800...
5.
Gasimli L, Hickey A, Yang B, Li G, Dela Rosa M, Nairn A, et al.
Biochim Biophys Acta
. 2014 Jan;
1840(6):1993-2003.
PMID: 24412195
Background: Proteoglycans are found on the cell surface and in the extracellular matrix, and serve as prime sites for interaction with signaling molecules. Proteoglycans help regulate pathways that control stem...
6.
Menendez L, Kulik M, Page A, Park S, Lauderdale J, Cunningham M, et al.
Nat Protoc
. 2013 Jan;
8(1):203-12.
PMID: 23288320
Multipotent neural crest stem cells (NCSCs) have the potential to generate a wide range of cell types including melanocytes; peripheral neurons; and smooth muscle, bone, cartilage and fat cells. This...
7.
McLean A, DAmour K, Jones K, Krishnamoorthy M, Kulik M, Reynolds D, et al.
Stem Cells
. 2007 Jan;
25(1):29-38.
PMID: 17204604
Human ESCs (hESCs) respond to signals that determine their pluripotency, proliferation, survival, and differentiation status. In this report, we demonstrate that phosphatidylinositol 3-kinase (PI3K) antagonizes the ability of hESCs to...
8.
Ludlow J, Bruce A, Kulik M, Meheux S, McCoy D, Asfeldt T
Prog Transplant
. 2005 Jul;
15(2):178-84.
PMID: 16013468
The scarcity of human organs available for transplantation is clearly evident. Efforts to maximize the use of available organs and to increase the number of donors have increased the number...