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Michael J Gerdes

Explore the profile of Michael J Gerdes including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 974
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Recent Articles
11.
Gerdes M
Proc Natl Acad Sci U S A . 2014 Feb; 111(2):E216. PMID: 24571024
No abstract available.
12.
Eifert C, Wang X, Kokabee L, Kourtidis A, Jain R, Gerdes M, et al.
Genes Chromosomes Cancer . 2013 Aug; 52(10):961-75. PMID: 23913792
Tyrosine kinases orchestrate key cellular signaling pathways and their dysregulation is often associated with cellular transformation. Several recent cases in which inhibitors of tyrosine kinases have been successfully used as...
13.
Gerdes M, Sevinsky C, Sood A, Adak S, Bello M, Bordwell A, et al.
Proc Natl Acad Sci U S A . 2013 Jul; 110(29):11982-7. PMID: 23818604
Limitations on the number of unique protein and DNA molecules that can be characterized microscopically in a single tissue specimen impede advances in understanding the biological basis of health and...
14.
Nelson D, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, et al.
Biol Open . 2013 Jun; 2(5):439-47. PMID: 23789091
Epithelial organ morphogenesis involves reciprocal interactions between epithelial and mesenchymal cell types to balance progenitor cell retention and expansion with cell differentiation for evolution of tissue architecture. Underlying submandibular salivary...
15.
Trempus C, Dang H, Humble M, Wei S, Gerdes M, Morris R, et al.
J Invest Dermatol . 2007 Jun; 127(12):2904-7. PMID: 17581618
No abstract available.
16.
Oh W, Rishi V, Orosz A, Gerdes M, Vinson C
Cancer Res . 2007 Feb; 67(4):1867-76. PMID: 17308129
The CCAAT/enhancer binding proteins (C/EBP) are a family of B-ZIP DNA binding proteins that act as transcription factors to regulate growth and differentiation of many cell types, including keratinocytes. To...
17.
Gerdes M, Yuspa S
Stem Cell Rev . 2006 Dec; 1(3):225-31. PMID: 17142859
Tumors arising from the skin are of multiple phenotypes, with differing degrees of malignant potential. In mouse models of skin carcinogenesis, tumors of squamous phenotype are the most common; however,...
18.
Gerdes M, Myakishev M, Frost N, Rishi V, Moitra J, Acharya A, et al.
Cancer Res . 2006 Aug; 66(15):7578-88. PMID: 16885357
To examine the consequences of inhibiting activator protein-1 (AP-1) transcription factors in skin, transgenic mice were generated, which use the tetracycline system to conditionally express A-FOS, a dominant negative that...
19.
Gerdes M, Larsen M, Dang T, Ressler S, Tuxhorn J, Rowley D
Prostate . 2004 Jan; 58(3):299-307. PMID: 14743470
Background: Myodifferentiation of stromal cells is a key step in prostate development and is a hallmark of reactive stroma in prostate cancer. Little is known about regulatory mechanisms, however, prostate...