Michael J Ernandes
Overview
Explore the profile of Michael J Ernandes including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
1222
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ernandes M, Kagan J
mBio
. 2021 Apr;
12(2).
PMID: 33849978
Mammalian cells detect microbial molecules known as pathogen-associated molecular patterns (PAMPs) as indicators of potential infection. Upon PAMP detection, diverse defensive responses are induced by the host, including those that...
2.
Barnett K, Coronas-Serna J, Zhou W, Ernandes M, Cao A, Kranzusch P, et al.
Cell
. 2019 Mar;
176(6):1432-1446.e11.
PMID: 30827685
The presence of DNA in the cytosol of mammalian cells is an unusual event that is often associated with genotoxic stress or viral infection. The enzyme cGAS is a sensor...
3.
Raymond D, Stewart S, Lee J, Ferdman J, Bajic G, Do K, et al.
Nat Med
. 2016 Nov;
22(12):1465-1469.
PMID: 27820604
For broad protection against infection by viruses such as influenza or HIV, vaccines should elicit antibodies that bind conserved viral epitopes, such as the receptor-binding site (RBS). RBS-directed antibodies have...
4.
Gorman J, Soto C, Yang M, Davenport T, Guttman M, Bailer R, et al.
Nat Struct Mol Biol
. 2015 Dec;
23(1):81-90.
PMID: 26689967
Broadly neutralizing antibodies (bNAbs) against HIV-1 Env V1V2 arise in multiple donors. However, atomic-level interactions had previously been determined only with antibodies from a single donor, thus making commonalities in...
5.
Doria-Rose N, Bhiman J, Roark R, Schramm C, Gorman J, Chuang G, et al.
J Virol
. 2015 Oct;
90(1):76-91.
PMID: 26468542
Unlabelled: The epitopes defined by HIV-1 broadly neutralizing antibodies (bNAbs) are valuable templates for vaccine design, and studies of the immunological development of these antibodies are providing insights for vaccination...
6.
Zhou T, Lynch R, Chen L, Acharya P, Wu X, Doria-Rose N, et al.
Cell
. 2015 May;
161(6):1280-92.
PMID: 26004070
The site on the HIV-1 gp120 glycoprotein that binds the CD4 receptor is recognized by broadly reactive antibodies, several of which neutralize over 90% of HIV-1 strains. To understand how...
7.
Doria-Rose N, Schramm C, Gorman J, Moore P, Bhiman J, DeKosky B, et al.
Nature
. 2014 Mar;
509(7498):55-62.
PMID: 24590074
Antibodies capable of neutralizing HIV-1 often target variable regions 1 and 2 (V1V2) of the HIV-1 envelope, but the mechanism of their elicitation has been unclear. Here we define the...