Michael J Dye
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Explore the profile of Michael J Dye including associated specialties, affiliations and a list of published articles.
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7
Citations
947
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Recent Articles
1.
Nojima T, Gomes T, Grosso A, Kimura H, Dye M, Dhir S, et al.
Cell
. 2015 Apr;
161(3):526-540.
PMID: 25910207
Transcription is a highly dynamic process. Consequently, we have developed native elongating transcript sequencing technology for mammalian chromatin (mNET-seq), which generates single-nucleotide resolution, nascent transcription profiles. Nascent RNA was detected...
2.
Nojima T, Dienstbier M, Murphy S, Proudfoot N, Dye M
Cell Rep
. 2013 Apr;
3(4):1080-92.
PMID: 23562152
Mammalian RNA polymerase II (Pol II) transcription termination is an essential step in protein-coding gene expression that is mediated by pre-mRNA processing activities and DNA-encoded terminator elements. Although much is...
3.
White E, Kamieniarz-Gdula K, Dye M, Proudfoot N
Nucleic Acids Res
. 2012 Dec;
41(3):1797-806.
PMID: 23258704
RNA Polymerase II (Pol II) termination is dependent on RNA processing signals as well as specific terminator elements located downstream of the poly(A) site. One of the two major terminator...
4.
West S, Proudfoot N, Dye M
Mol Cell
. 2008 Mar;
29(5):600-10.
PMID: 18342606
Transcriptional termination of mammalian RNA polymerase II (Pol II) is an essential but little-understood step in protein-coding gene expression. Mechanistically, termination by all DNA-dependent RNA polymerases can be reduced to...
5.
Dye M, Gromak N, Proudfoot N
Mol Cell
. 2006 Mar;
21(6):849-59.
PMID: 16543153
There is an emerging consensus that RNA polymerase II (RNA Pol II) transcription and pre-mRNA processing are tightly coupled events. We show here that exons flanking an intron that has...
6.
Plant K, Dye M, Lafaille C, Proudfoot N
Mol Cell Biol
. 2005 Mar;
25(8):3276-85.
PMID: 15798211
The human gamma-globin genes form part of a 5-kb tandem duplication within the beta-globin gene cluster on chromosome 11. Despite a high degree of identity between the two genes, we...
7.
Proudfoot N, Furger A, Dye M
Cell
. 2002 Mar;
108(4):501-12.
PMID: 11909521
The messenger RNA processing reactions of capping, splicing, and polyadenylation occur cotranscriptionally. They not only influence one another's efficiency and specificity, but are also coordinated by transcription. The phosphorylated CTD...