Michael J Doenhoff
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Explore the profile of Michael J Doenhoff including associated specialties, affiliations and a list of published articles.
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47
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1672
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Recent Articles
11.
Igetei J, Liddell S, El-Faham M, Doenhoff M
Parasitology
. 2016 Mar;
143(5):646-57.
PMID: 26924446
A serine protease-like enzyme found in detergent extracts of Schistosoma mansoni adult worms perfused from infected mice has been purified from mouse blood and further characterized. The enzyme is approximately...
12.
Wan D, Ludolf F, Alanine D, Stretton O, Ali E, Al-Barwary N, et al.
PLoS Negl Trop Dis
. 2014 Sep;
8(9):e3124.
PMID: 25254513
Background: Parasite-specific IgE is thought to correlate with protection against Schistosoma mansoni infection or re-infection. Only a few molecular targets of the IgE response in S. mansoni infection have been...
13.
Nausch N, Dawson E, Midzi N, Mduluza T, Mutapi F, Doenhoff M
BMC Infect Dis
. 2014 Mar;
14:165.
PMID: 24666689
Background: Rapid diagnostic tests (RDTs) for use at the point-of-care (POC) are likely to become increasingly useful as large-scale control programmes for schistosomiasis get underway. Given the low sensitivity of...
14.
Dawson E, Sousa-Figueiredo J, Kabatereine N, Doenhoff M, Stothard J
Trans R Soc Trop Med Hyg
. 2013 Aug;
107(10):639-47.
PMID: 23976783
Background: A sensitive and reliable rapid diagnostic test (RDT) which should have comparable diagnostic performance against reference host serological methods is urgently needed for use in point-of-care (POC) diagnosis of...
15.
Coulibaly J, NGoran E, Utzinger J, Doenhoff M, Dawson E
Parasit Vectors
. 2013 Jan;
6:29.
PMID: 23360734
Background: Parasitological methods are widely used for the diagnosis of schistosomiasis. However, they are insensitive, particularly in areas of low endemicity, and labour-intensive. Immunoassays based on detection of anti-schistosome antibodies...
16.
Zaccone P, Burton O, Gibbs S, Miller N, Jones F, Schramm G, et al.
Eur J Immunol
. 2011 Jun;
41(9):2709-18.
PMID: 21710488
Immunization with Schistosoma mansoni soluble antigen preparations protects non-obese diabetic (NOD) mice against the development of type 1 diabetes. These preparations have long been known to induce Th2 responses in...
17.
Meevissen M, Balog C, Koeleman C, Doenhoff M, Schramm G, Haas H, et al.
Mol Cell Proteomics
. 2011 Mar;
10(5):M110.005710.
PMID: 21372247
Glycans present on glycoproteins from the eggs of the parasite Schistosoma mansoni are mediators of various immune responses of the human host, including T-cell modulation and granuloma formation, and they...
18.
El Aswad B, Doenhoff M, El Hadidi A, Schwaeble W, Lynch N
Immunobiology
. 2010 Aug;
216(3):379-85.
PMID: 20691496
Schistosomiasis is traditionally diagnosed by microscopic detection of ova in stool samples, but this method is labour intensive and its sensitivity is limited by low and variable egg secretion in...
19.
Lehr T, Frank S, Natsuka S, Geyer H, Beuerlein K, Doenhoff M, et al.
Exp Parasitol
. 2010 Jul;
126(4):592-602.
PMID: 20599986
Comparative analyses of the N-glycosylation pattern of hemolymph glycoproteins from Biomphalaria glabrata strains Puerto Rico (BgPR) and Salvador (BgBS-90), differing in their susceptibility towards Schistosoma mansoni infection, were performed by...
20.
Meevissen M, Wuhrer M, Doenhoff M, Schramm G, Haas H, Deelder A, et al.
J Proteome Res
. 2010 Feb;
9(5):2630-42.
PMID: 20178377
Soluble egg antigens (SEA) of the human parasite Schistosoma mansoni are among the strongest natural stimuli of Th2 responses. Omega-1, a major glycoprotein in SEA, initiates these characteristic Th2 responses...