Michael J Doenhoff
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Explore the profile of Michael J Doenhoff including associated specialties, affiliations and a list of published articles.
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47
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1672
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Recent Articles
1.
Arndts K, Elfaki T, Doenhoff M, Katawa G, Goreish I, Atti El Mekki M, et al.
Pathogens
. 2022 Jan;
11(1).
PMID: 35055967
Despite the existence of an effective medication against schistosomiasis, the disease remains a major health problem in affected areas, especially for those lacking appropriate sanitary facilities. Moreover, treatment cannot prevent...
2.
El-Faham M, Gai F, Igetei J, Richter S, Falcone F, Schramm G, et al.
Sci Rep
. 2020 May;
10(1):8623.
PMID: 32433571
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
3.
El-Faham M, Gai F, Igetei J, Richter S, Falcone F, Schramm G, et al.
Sci Rep
. 2020 Feb;
10(1):3350.
PMID: 32099050
Previous studies have shown that rabbit IgG antibodies against Schistosoma mansoni egg antigens (SmSEA) cross-react with allergens in natural rubber latex, peanuts and grass and tree pollens. Here we describe...
4.
Doenhoff M, Modha J, Walker A
Int J Parasitol
. 2019 Jul;
49(10):747-757.
PMID: 31348959
When adult schistosome worm pairs are transferred from experimental hosts to in vitro culture they cease producing viable eggs within a few days. Female worms in unisexual infections fail to...
5.
Knuhr K, Langhans K, Nyenhuis S, Viertmann K, Kildemoes A, Doenhoff M, et al.
Front Immunol
. 2018 Oct;
9:2293.
PMID: 30364177
Schistosomes control inflammation in their hosts highly effective mechanisms such as induction of Tregs, Bregs, and alternatively activated macrophages (AAMs). Notably, IPSE/alpha-1, the major secretory product from eggs, triggers basophils...
6.
Igetei J, El-Faham M, Liddell S, Schramm G, Doenhoff M
Int J Parasitol
. 2018 Mar;
48(5):345-357.
PMID: 29510117
Previous studies have shown that schistosome infection can protect against allergic symptoms, but the underlying mechanisms are still not fully understood. Here we have shown that rabbit IgG antibodies raised...
7.
El-Faham M, Eissa M, Igetei J, Amer E, Liddell S, El-Azzouni M, et al.
PLoS Negl Trop Dis
. 2017 Aug;
11(8):e0005853.
PMID: 28841653
Background: Miltefosine, an anti-cancer drug that has been successfully repositioned for treatment of Leishmania infections, has recently also shown promising effects against Schistosoma spp targeting all life cycle stages of...
8.
El-Faham M, Wheatcroft-Francklow K, Price H, Sayers J, Doenhoff M
Parasitology
. 2017 Aug;
144(10):1356-1364.
PMID: 28777067
The Schistosoma mansoni cercarial elastase (SmCE) has previously been shown to be poorly immunogenic in mice. However, a minority of mice were able to produce antibodies against SmCE after multiple...
9.
Igetei J, El-Faham M, Liddell S, Doenhoff M
Immunology
. 2017 Feb;
150(4):506-517.
PMID: 28201853
The antigenic reactivity of constituents of Schistosoma mansoni and peanut (Arachis hypogaea) was investigated to determine whether identical antigenic epitopes possessed by both organisms provided a possible explanation for the...
10.
Doenhoff M, El-Faham M, Liddell S, Fuller H, Stanley R, Schramm G, et al.
PLoS One
. 2016 Jul;
11(7):e0159542.
PMID: 27467385
IgG antibodies produced by rabbits immunized against S. mansoni antigens cross-reacted with aqueous soluble constituents of a variety of allergens. The antibody cross-reactivity was largely sensitive to degradation by treatment...