Michael J Darsley
Overview
Explore the profile of Michael J Darsley including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
274
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chakraborty S, Randall A, Vickers T, Molina D, Harro C, DeNearing B, et al.
NPJ Vaccines
. 2019 Sep;
4:37.
PMID: 31482013
Enterotoxigenic (ETEC) infections are a common cause of severe diarrheal illness in low- and middle-income countries. The live-attenuated ACE527 ETEC vaccine, adjuvanted with double mutant heat-labile toxin (dmLT), affords clear...
2.
Harro C, Louis Bourgeois A, Sack D, Walker R, DeNearing B, Brubaker J, et al.
Vaccine
. 2019 Feb;
37(14):1978-1986.
PMID: 30797634
Background: There is no licensed vaccine against enterotoxigenic Escherichia coli (ETEC), a major cause of diarrhea-associated morbidity and mortality among infants and children in low-income countries and travelers. The results...
3.
Chakraborty S, Randall A, Vickers T, Molina D, Harro C, DeNearing B, et al.
J Infect Dis
. 2018 May;
218(9):1436-1446.
PMID: 29800314
Background: Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrheal illness in the developing world. Enterotoxigenic E coli vaccinology has been challenged by genetic diversity and heterogeneity of canonical...
4.
Lal M, Priddy S, Bourgeois L, Walker R, Pebley W, Brown J, et al.
Vaccine
. 2013 Aug;
31(42):4759-64.
PMID: 23965220
Vaccination is considered the most cost-effective approach to preventing infectious diseases, yet better formulations and delivery methods for efficient distribution and administration of vaccines are needed, especially for low-resource settings....
5.
Darsley M, Chakraborty S, DeNearing B, Sack D, Feller A, Buchwaldt C, et al.
Clin Vaccine Immunol
. 2012 Oct;
19(12):1921-31.
PMID: 23035175
An oral, live attenuated, three-strain recombinant bacterial vaccine, ACE527, was demonstrated to generate strong immune responses to colonization factor and toxin antigens of enterotoxigenic Escherichia coli (ETEC) in human volunteers....
6.
Turner A, Stephens J, Beavis J, Greenwood J, Gewert C, Randall R, et al.
Clin Vaccine Immunol
. 2011 Oct;
18(12):2128-35.
PMID: 21994355
Live attenuated oral enterotoxigenic Escherichia coli (ETEC) vaccines have been demonstrated to be safe and immunogenic in human volunteers and to provide a viable approach to provide protection against this...
7.
Harro C, Sack D, Louis Bourgeois A, Walker R, DeNearing B, Feller A, et al.
Clin Vaccine Immunol
. 2011 Oct;
18(12):2118-27.
PMID: 21994354
Immune responses against colonization factors (CFs) and the nontoxic B component of the enterotoxigenic Escherichia coli (ETEC) heat-labile toxin (LTB) are considered to be important for immunity against diarrhea caused...
8.
Stephens J, Darsley M, Turner A
Infect Immun
. 2006 Jun;
74(7):4383-6.
PMID: 16790817
A gene cassette incorporating the crs-rsd site-specific recombination system from the Salmonella enterica subsp. enterica serovar Dublin virulence plasmid improved the inheritance in S. enterica serotype Typhi strain CVD908-htrA of...
9.
Turner A, Beavis J, Stephens J, Greenwood J, Gewert C, Thomas N, et al.
Infect Immun
. 2006 Jan;
74(2):1062-71.
PMID: 16428753
Oral delivery of toxin-negative derivatives of enterotoxigenic Escherichia coli (ETEC) that express colonization factor antigens (CFA) with deletions of the aroC, ompC, ompF, and toxin genes may be an effective...
10.
Londono-Arcila P, Freeman D, Kleanthous H, ODowd A, Lewis S, Turner A, et al.
Infect Immun
. 2002 Aug;
70(9):5096-106.
PMID: 12183559
Recombinant vaccine strains of Salmonella enterica serovar Typhi capable of expressing Helicobacter pylori urease were generated by transforming strains CVD908 and CVD908-htrA with a plasmid harboring the ureAB genes under...