Michael J Bernas
Overview
Explore the profile of Michael J Bernas including associated specialties, affiliations and a list of published articles.
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9
Citations
271
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Recent Articles
1.
Mustacich D, Lai L, Bernas M, Jones J, Myles R, Kuo P, et al.
Am J Med
. 2021 Oct;
135(2):e31-e41.
PMID: 34656527
Background: The lymphatic system is essential for maintaining the balance of interstitial fluid in tissues and for returning protein-rich fluids (lymph) to the bloodstream. Congenital lymphatic defects lead to accumulation...
2.
Erickson R, Lai L, Mustacich D, Bernas M, Kuo P, Witte M
Clin Genet
. 2019 Aug;
96(5):478-482.
PMID: 31403174
A second multigeneration family with hereditary lymphedema (LE) secondary to a variant in the planar polarity gene, CELSR1, is described. Dominant inheritance of the variant was discovered using whole-exome sequencing...
3.
McCallum A, Gallek M, Ramey W, Manziello A, Witte M, Bernas M, et al.
Pathophysiology
. 2016 Jun;
23(3):181-90.
PMID: 27354343
Introduction: Despite being one of the most common neurological diseases, it is unknown whether there may be a genetic basis to temporal lobe epilepsy (TLE). Whole genome analyses were performed...
4.
Funk J, Frye J, Davis-Gorman G, Spera A, Bernas M, Witte M, et al.
Microcirculation
. 2013 Mar;
20(6):544-54.
PMID: 23464666
Objective: We sought to test the hypothesis that turmeric-derived curcuminoids limit reperfusion brain injury in an experimental model of stroke via blockade of early microvascular inflammation during reperfusion. Methods: Male...
5.
Shimoda H, Bernas M, Witte M
Histochem Cell Biol
. 2011 May;
135(6):603-13.
PMID: 21614587
Dysmorphogenesis of lymph nodes displayed in a fork head transcription factor Foxc2 haploinsufficient mice--a model for lymphedema-distichiasis syndrome--was studied by immunohistochemistry and electron microscopy. The Foxc2 heterozygous mice manifested lymph...
6.
Bernas M, Cardoso F, Daley S, Weinand M, Campos A, Goncalves Ferreira A, et al.
Nat Protoc
. 2010 Jul;
5(7):1265-72.
PMID: 20595955
We describe a method for generating primary cultures of human brain microvascular endothelial cells (HBMVECs). HBMVECs are derived from microvessels isolated from temporal tissue removed during operative treatment of epilepsy....
7.
Dellinger M, Hunter R, Bernas M, Witte M, Erickson R
Dev Dyn
. 2007 Jun;
236(8):2346-55.
PMID: 17584866
Recent advances in molecular lymphology and lymphatic phenotyping techniques in small animals offer new opportunities to delineate mutant mouse models. Chy-3 mutant mice were originally named for their chylous ascites,...
8.
Shimoda H, Bernas M, Witte M, Gale N, Yancopoulos G, Kato S
Cell Tissue Res
. 2007 Jan;
328(2):329-37.
PMID: 17235601
The fine structure of lymphatic capillaries in the digestive organs of angiopoietin-2 (Ang2) knockout mice was studied by using both immunohistochemistry and electron microscopy. The genetic deletion of Ang2 yielded...
9.
Kriederman B, Myloyde T, Witte M, Dagenais S, Witte C, Rennels M, et al.
Hum Mol Genet
. 2003 Apr;
12(10):1179-85.
PMID: 12719382
Lymphedema-distichiasis (LD) (OMIM 153400) is a rare autosomal-dominant condition characterized by pubertal onset of lower limb lymphedema and an aberrant second row of eyelashes arising from the meibomian glands. In...