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Michael J Avram

Explore the profile of Michael J Avram including associated specialties, affiliations and a list of published articles. Areas
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Articles 99
Citations 1436
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Recent Articles
1.
Choi W, Fattah M, Shang Y, Thompson M, Carrow K, Hu D, et al.
Sci Adv . 2024 Nov; 10(44):eado8307. PMID: 39485846
Recently, it has been shown that blocking the binding of valosin-containing protein (VCP) to mutant huntingtin (mtHtt) can prevent neuronal mitochondrial autophagy in Huntington's disease (HD) models. Herein, we describe...
2.
Berger O, Choi W, Ko C, Thompson M, Avram M, Scott D, et al.
ACS Pharmacol Transl Sci . 2024 May; 7(5):1252-1261. PMID: 38751631
Hepatorenal syndrome (HRS) is a life-threatening complication of end-stage liver disease first reported over a century ago, but its management still poses an unmet challenge. A therapeutic agent found to...
3.
Wisner K, Avram M, George Jr A, Abramova T, Yang A, Caritis S, et al.
J Clin Psychopharmacol . 2024 Feb; 44(2):100-106. PMID: 38421920
Rationale: Few studies of the effect of the dynamic physiologic changes during pregnancy on plasma concentrations of fluoxetine (FLX) have been published. Objectives: We determined the change in concentration to...
4.
Mesches G, Ciolino J, Stika C, Sit D, Zumpf K, Fisher S, et al.
Psychiatr Res Clin Pract . 2022 Oct; 4(2):32-41. PMID: 36254188
Objective: Tracking perinatal mood and anxiety disorders is championed by the American Psychiatric Association and the International Marcé Society for Perinatal Mental Health. We conducted this study to examine trajectories...
5.
Stika C, Wisner K, George Jr A, Avram M, Zumpf K, Rasmussen-Torvik L, et al.
Clin Pharmacol Ther . 2022 Sep; 112(6):1280-1290. PMID: 36094046
Major depressive disorder (MDD) is a common disorder in pregnancy. Although sertraline is the most frequently prescribed antidepressant for pregnant people in the United States, limited information about its pharmacokinetics...
6.
Kumthekar P, Avram M, Lassman A, Lin N, Lee E, Grimm S, et al.
Neuro Oncol . 2022 Aug; 25(3):557-565. PMID: 35948282
Background: Patients with human epidermal growth factor receptor 2-positive (HER2-positive) cancers have a high incidence of central nervous system (CNS) spread, but unfortunately systemic trastuzumab which targets the HER2 receptor...
7.
Clark C, Newmark R, Wisner K, Stika C, Avram M
J Clin Pharmacol . 2022 May; 62(11):1385-1392. PMID: 35620848
The pharmacokinetics of lithium, the gold standard for the treatment of bipolar disorder, are well described in nonpregnant patients. Because lithium is commonly prescribed to women of childbearing age, more...
8.
Henthorn T, Krejcie T, Avram M
Anesthesiology . 2021 Dec; 136(2):258-260. PMID: 34965290
No abstract available.
9.
Kharasch E, Avram M, Bateman B, Clark J, Culley D, Davidson A, et al.
Anesthesiology . 2021 May; 135(1):1-8. PMID: 34046664
No abstract available.
10.
Murphy G, Avram M, Greenberg S, Benson J, Bilimoria S, Maher C, et al.
Anesthesiology . 2021 Mar; 134(5):697-708. PMID: 33730151
Background: Despite application of multimodal pain management strategies, patients undergoing spinal fusion surgery frequently report severe postoperative pain. Methadone and ketamine, which are N-methyl-d-aspartate receptor antagonists, have been documented to...