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Michael Hartmann

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Articles 122
Citations 2200
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Recent Articles
1.
Hartmann M, Rauscher M, Robinson J, Welsh J, Roush D
J Chromatogr A . 2025 Mar; 1747:465818. PMID: 40023049
The development of robust polishing chromatographic processes is a critical step in downstream bioprocess development that can be time-consuming and resource intensive. Recently, there has been an increase in diverse...
2.
Robinson J, Vats M, Hartmann M
J Chromatogr A . 2025 Feb; 1746:465784. PMID: 39983562
Flow through anion exchange chromatography (AEX) has provided reliable process-and product-related impurities removal as well as viral clearance for monoclonal antibodies (mAbs). The application of AEX to molecules with more...
3.
Hartmann M, Kirchner J, Kovacevic T
Praxis (Bern 1994) . 2025 Feb; 114(1):30-33. PMID: 39964379
Reducing pain is an indubitable ethical requirement; the need for pain treatment is compelling. Modern pain therapy should take place in an interdisciplinary context in order to use the advantages...
4.
Kather A, Arefian H, Schneider C, Hartmann M, Runnebaum I
PLoS Med . 2025 Jan; 22(1):e1004514. PMID: 39883621
Background: There is indication that the fallopian tubes might be involved in ovarian cancer pathogenesis and their removal reduces cancer risk. Hence, bilateral salpingectomy during hysterectomy or sterilization, so called...
5.
Stuart A, Wagenius J, Badiglian-Filho L, Schnabel J, Montealegre A, Ehrstrom S, et al.
BJOG . 2024 Nov; 132(4):464-472. PMID: 39552409
Objective: To present the rates of intra- and postoperative complications and conversions in a large cohort of unselected vNOTES hysterectomies, performed by surgeons with different levels of expertise. Design: International...
6.
Andrikyan W, Sponfeldner M, Jung-Poppe L, Durr P, Straubmeier M, Schuster A, et al.
Br J Clin Pharmacol . 2024 Nov; 91(3):829-840. PMID: 39511858
Aims: Previous work has identified several limitations in "Summaries of Product Characteristics" (SmPCs), which are associated with risks for patients. The aim of this study was to evaluate pharmacists' and...
7.
Scholten N, Hartmann M, Abts S, Abts L, Reinartz E, Altavilla A, et al.
J Biol Chem . 2024 Aug; 300(9):107667. PMID: 39128721
Isochorismate-derived metabolism enables biosynthesis of the plant defense hormone salicylic acid (SA) and its derivatives. In Arabidopsis thaliana, the stress-induced accumulation of SA depends on ISOCHORISMATE SYNTHASE1 (ICS1) and also...
8.
Liu P, Hartmann M, Shankaran A, Li H, Welsh J
Biotechnol Bioeng . 2024 Jun; 121(9):2924-2935. PMID: 38837221
Advances in upstream production of biologics-particularly intensified fed-batch processes beyond 10% cell solids-have severely strained harvest operations, especially depth filtration. Bioreactors containing high amounts of cell debris (more than 40%...
9.
Schwarz F, Arefian H, Hartmann M, Runnebaum I
PLoS One . 2024 May; 19(5):e0303776. PMID: 38722867
[This corrects the article DOI: 10.1371/journal.pone.0278460.].
10.
Chevalier Q, Huchelmann A, Debie P, Mercier P, Hartmann M, Vonthron-Senecheau C, et al.
Plants (Basel) . 2024 Apr; 13(8). PMID: 38674519
In plants, the plastidial mevalonate (MVA)-independent pathway is required for the modification with geranylgeranyl groups of CaaL-motif proteins, which are substrates of protein geranylgeranyltransferase type-I (PGGT-I). As a consequence, fosmidomycin,...