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Michael H Myoga

Explore the profile of Michael H Myoga including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 343
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Recent Articles
1.
Natarajan P, Koupourtidou C, de Resseguier T, Thorwirth M, Bocchi R, Fischer-Sternjak J, et al.
Glia . 2024 Nov; 73(4):737-758. PMID: 39610085
Astrocytes play key roles in brain function, but how these are orchestrated by transcription factors (TFs) in the adult brain and aligned with astrocyte heterogeneity is largely unknown. Here we...
2.
Bednarova V, Grothe B, Myoga M
J Physiol . 2018 Sep; 596(21):5281-5298. PMID: 30206945
Key Points: Although the visual circuits in the superior colliculus (SC) have been thoroughly examined, the auditory circuits lack equivalent scrutiny. SC neurons receiving auditory inputs in mice were characterized...
3.
Petrik D, Myoga M, Grade S, Gerkau N, Pusch M, Rose C, et al.
Cell Stem Cell . 2018 May; 22(6):865-878.e8. PMID: 29779889
One hallmark of adult neurogenesis is its adaptability to environmental influences. Here, we uncovered the epithelial sodium channel (ENaC) as a key regulator of adult neurogenesis as its deletion in...
4.
Beiderbeck B, Myoga M, Muller N, Callan A, Friauf E, Grothe B, et al.
Nat Commun . 2018 May; 9(1):1771. PMID: 29720589
The integration of excitatory and inhibitory synaptic inputs is fundamental to neuronal processing. In the mammalian auditory brainstem, neurons compare excitatory and inhibitory inputs from the ipsilateral and contralateral ear,...
5.
Myoga M, Lehnert S, Leibold C, Felmy F, Grothe B
Nat Commun . 2014 May; 5:3790. PMID: 24804642
Neurons in the medial superior olive (MSO) detect microsecond differences in the arrival time of sounds between the ears (interaural time differences or ITDs), a crucial binaural cue for sound...
6.
Morgan D, Davis B, Kearn C, Marcus D, Cook A, Wager-Miller J, et al.
J Neurosci . 2014 Apr; 34(15):5152-63. PMID: 24719095
For many G-protein-coupled receptors (GPCRs), including cannabinoid receptor 1 (CB1R), desensitization has been proposed as a principal mechanism driving initial tolerance to agonists. GPCR desensitization typically requires phosphorylation by a...
7.
Stange A, Myoga M, Lingner A, Ford M, Alexandrova O, Felmy F, et al.
Nat Neurosci . 2013 Oct; 16(12):1840-7. PMID: 24141311
Across all sensory modalities, the effect of context-dependent neural adaptation can be observed at every level, from receptors to perception. Nonetheless, it has long been assumed that the processing of...
8.
Fioravante D, Myoga M, Leitges M, Regehr W
J Neurosci . 2012 Sep; 32(38):13004-9. PMID: 22993418
Posttetanic potentiation (PTP) is a transient, calcium-dependent increase in the efficacy of synaptic transmission following elevated presynaptic activity. The calcium-dependent protein kinase C (PKC(Ca)) isoforms PKCα and PKCβ mediate PTP...
9.
Fioravante D, Chu Y, Myoga M, Leitges M, Regehr W
Neuron . 2011 Jun; 70(5):1005-19. PMID: 21658591
High-frequency stimulation leads to a transient increase in the amplitude of evoked synaptic transmission that is known as posttetanic potentiation (PTP). Here we examine the roles of the calcium-dependent protein...
10.
Myoga M, Regehr W
J Neurosci . 2011 Apr; 31(14):5235-43. PMID: 21471358
R-type calcium channels in postsynaptic spines signal through functional calcium microdomains to regulate a calcium/calmodulin-sensitive potassium channel that in turn regulates postsynaptic hippocampal long-term potentiation (LTP). Here, we ask whether...