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Michael Groot

Explore the profile of Michael Groot including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 424
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Recent Articles
1.
Carnino J, Lee H, He X, Groot M, Jin Y
Cell Death Discov . 2020 Sep; 6:82. PMID: 32963810
Acute respiratory distress syndrome (ARDS) is a devastating syndrome responsible for significant morbidity and mortality. Diffuse alveolar epithelial cell death, including but not limited to apoptosis and necroptosis, is one...
2.
Groot M, Lee H
Cells . 2020 Apr; 9(4). PMID: 32331346
Extracellular vesicles (EV) are secretory membranous elements used by cells to transport proteins, lipids, mRNAs, and microRNAs (miRNAs). While their existence has been known for many years, only recently has...
3.
Zhang D, Lee H, Wang X, Groot M, Sharma L, Dela Cruz C, et al.
Thorax . 2019 Jul; 74(9):865-874. PMID: 31331947
Background: Uncontrolled lung inflammation is one of the prominent features in the pathogenesis of lung infection- associated acute lung injury (ALI). Microvesicles (MVs) are extracellular nanovesicles that are generated via...
4.
Groot M, Zhang D, Jin Y
JSM Bioinform Genom Proteom . 2019 Mar; 3(2). PMID: 30854513
Non-coding genes occupy the majority of the human genome and have recently garnered increased attention for their implications in a range of diseases. This review illustrates the current scientific landscape...
5.
Lee H, Groot M, Pinilla-Vera M, Fredenburgh L, Jin Y
J Control Release . 2018 Dec; 294:43-52. PMID: 30529727
Despite emerging interest in the role of extracellular vesicle (EV)-containing microRNAs (EV-miRNAs), the existence of functional EV-miRNAs under patho-physiological conditions has been viewed with skepticism. Due to the heterogenicity of...
6.
Zhang D, Lee H, Wang X, Rai A, Groot M, Jin Y
Mol Ther . 2018 Jul; 26(9):2119-2130. PMID: 30005869
Exosomes (EXOs) are a type of extracellular nanovesicles released from living cells. Accumulating evidence suggests that EXOs are involved in the pathogenesis of human diseases, including lung conditions. In recent...