Michael Goulding
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Explore the profile of Michael Goulding including associated specialties, affiliations and a list of published articles.
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11
Citations
129
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Recent Articles
1.
Correa S, van der Sleen P, Siddiqui S, Bogota-Gregory J, Arantes C, Barnett A, et al.
Bioscience
. 2022 Aug;
72(8):753-768.
PMID: 35923189
Riverine floodplains are biologically diverse and productive ecosystems. Although tropical floodplains remain relatively conserved and ecologically functional compared to those at higher latitudes, they face accelerated hydropower development, climate change,...
2.
Heilpern S, Sethi S, Barthem R, Batista V, Doria C, Duponchelle F, et al.
Proc Biol Sci
. 2022 Jun;
289(1976):20220726.
PMID: 35673861
Inland fisheries feed greater than 150 million people globally, yet their status is rarely assessed due to their socio-ecological complexity and pervasive lack of data. Here, we leverage an unprecedented...
3.
Prestes L, Barthem R, Mello-Filho A, Anderson E, Correa S, Couto T, et al.
PLoS One
. 2022 Mar;
17(3):e0264490.
PMID: 35235610
Migratory species are the most important commercial fishes in the Amazon. They are also now the most threatened directly by some combination of overfishing, floodplain deforestation, and dam construction. Limited...
4.
Flecker A, Shi Q, Almeida R, Angarita H, Gomes-Selman J, Garcia-Villacorta R, et al.
Science
. 2022 Feb;
375(6582):753-760.
PMID: 35175810
Proposed hydropower dams at more than 350 sites throughout the Amazon require strategic evaluation of trade-offs between the numerous ecosystem services provided by Earth's largest and most biodiverse river basin....
5.
McLeary F, Rcom-Hcheo-Gauthier A, Goulding M, Radford R, Okita Y, Faller P, et al.
Cells
. 2019 Feb;
8(2).
PMID: 30791479
The formation of cytotoxic intracellular protein aggregates is a pathological signature of multiple neurodegenerative diseases. The principle aggregating protein in Parkinson's disease (PD) and atypical Parkinson's diseases is α-synuclein (α-syn),...
6.
Valdinocci D, Radford R, Goulding M, Hayashi J, Chung R, Pountney D
Int J Mol Sci
. 2018 Dec;
19(12).
PMID: 30572656
Multiple system atrophy, characterized by atypical Parkinsonism, results from central nervous system (CNS) cell loss and dysfunction linked to aggregates of the normally pre-synaptic α-synuclein protein. Mostly cytoplasmic pathological α-synuclein...
7.
McLeary F, Rcom-Hcheo-Gauthier A, Kinder J, Goulding M, Khoo T, Mellick G, et al.
Neurotox Res
. 2017 Oct;
33(2):229-238.
PMID: 29064068
Intracellular aggregates of α-synuclein are the pathological hallmark of Parkinson's disease (PD) and dementia with Lewy bodies (DLB), being linked to neurotoxicity. Multiple triggers of α-synuclein aggregation have been implicated,...
8.
Forsberg B, Melack J, Dunne T, Barthem R, Goulding M, Paiva R, et al.
PLoS One
. 2017 Aug;
12(8):e0182254.
PMID: 28832638
Increased energy demand has led to plans for building many new dams in the western Amazon, mostly in the Andean region. Historical data and mechanistic scenarios are used to examine...
9.
Okita Y, Rcom-Hcheo-Gauthier A, Goulding M, Chung R, Faller P, Pountney D
Front Neurosci
. 2017 Apr;
11:114.
PMID: 28420950
Metallothioneins (MTs) are proteins that function by metal exchange to regulate the bioavailability of metals, such as zinc and copper. Copper functions in the brain to regulate mitochondria, neurotransmitter production,...
10.
Barthem R, Goulding M, Leite R, Canas C, Forsberg B, Venticinque E, et al.
Sci Rep
. 2017 Feb;
7:41784.
PMID: 28165499
We mapped the inferred long-distance migrations of four species of Amazonian goliath catfishes (Brachyplatystoma rousseauxii, B. platynemum, B. juruense and B. vaillantii) based on the presence of individuals with mature...