Michael G Rosenblum
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Explore the profile of Michael G Rosenblum including associated specialties, affiliations and a list of published articles.
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74
Citations
1503
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Recent Articles
1.
Mohamedali K, Aguirre B, Lu C, Chandla A, Kejriwal N, Liu L, et al.
J Immunother Cancer
. 2025 Jan;
12(12.
PMID: 39794935
Background: Granzyme B (GrB) is a key effector molecule, delivered by cytotoxic T lymphocytes and natural killer cells during immune surveillance to induce cell death. Fusion proteins and immunoconjugates represent...
2.
Alvarez de Cienfuegos A, Cheung L, Mohamedali K, Whitsett T, Winkles J, Hittelman W, et al.
J Immunother Cancer
. 2020 Sep;
8(2).
PMID: 32958685
Background: Antibody-drug conjugates are an exceptional and useful therapeutic tool for multiple diseases, particularly for cancer treatment. We previously showed that the fusion of the serine protease granzyme B (GrB),...
3.
Brown K, Meader L, Nowocin A, Edwards L, Cheung L, Smith R, et al.
J Immunol Methods
. 2020 May;
483:112794.
PMID: 32428450
A commonly employed method to determine the function of a particular cell population and to assess its contribution to the overall system in vivo is to selectively deplete that population...
4.
Olsen C, Cheung L, Weyergang A, Berg K, Vallera D, Rosenblum M, et al.
J Clin Med
. 2020 Jan;
9(1).
PMID: 31888091
The objective of this study was to develop and explore a novel CD133-targeting immunotoxin (IT) for use in combination with the endosomal escape method photochemical internalization (PCI). scFvCD133/rGelonin was recombinantly...
5.
Cheung L, Zhao Y, Alvarez-Cienfuegos A, Mohamedali K, Cao Y, Hittelman W, et al.
J Exp Clin Cancer Res
. 2019 Aug;
38(1):332.
PMID: 31362764
Background: Immunotherapeutic approaches designed to augment T and B cell mediated killing of tumor cells has met with clinical success in recent years suggesting tremendous potential for treatment in a...
6.
Weyergang A, Fremstedal A, Skarpen E, Peng Q, Mohamedali K, Eng M, et al.
J Control Release
. 2018 Sep;
288:161-172.
PMID: 30217739
Interactions between stromal cells and tumor cells pay a major role in cancer growth and progression. This is reflected in the composition of anticancer drugs which includes compounds directed towards...
7.
Redis R, Vela L, Lu W, de Oliveira J, Ivan C, Rodriguez-Aguayo C, et al.
Mol Cell
. 2017 Sep;
61(4):640.
PMID: 28934601
No abstract available.
8.
Mohamedali K, Rosenblum M
Biomedicines
. 2017 Jul;
5(3).
PMID: 28714916
Angiogenesis is a critical process in numerous diseases, and intervention in neovascularization has therapeutic value in several disease settings, including ocular diseases, arthritis, and in tumor progression and metastatic spread....
9.
Pincus S, Song K, Maresh G, Frank A, Worthylake D, Chung H, et al.
J Virol
. 2016 Nov;
91(3).
PMID: 27795412
Importance: It is not yet possible to cure HIV infection. Even after years of fully effective antiviral therapy, a persistent reservoir of virus-infected cells remains. Here we propose that a...
10.
Redis R, Vela L, Lu W, de Oliveira J, Ivan C, Rodriguez-Aguayo C, et al.
Mol Cell
. 2016 Feb;
61(4):520-534.
PMID: 26853146
Altered energy metabolism is a cancer hallmark as malignant cells tailor their metabolic pathways to meet their energy requirements. Glucose and glutamine are the major nutrients that fuel cellular metabolism,...