Michael G Drage
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Explore the profile of Michael G Drage including associated specialties, affiliations and a list of published articles.
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46
Citations
831
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Recent Articles
1.
Abel J, Jain S, Rajan D, Padigela H, Leidal K, Prakash A, et al.
NPJ Precis Oncol
. 2024 Jun;
8(1):134.
PMID: 38898127
While alterations in nucleus size, shape, and color are ubiquitous in cancer, comprehensive quantification of nuclear morphology across a whole-slide histologic image remains a challenge. Here, we describe the development...
2.
Huang C, Montague J, Ching-Roa V, Drage M, Ibrahim S, Giacomelli M
Biomed Opt Express
. 2024 Feb;
15(2):700-714.
PMID: 38404330
Tissue clearing methods render biological tissues transparent while maintaining tissue structure, enabling visualization of entire tissues. Recent developments in tissue clearing have predominantly emphasized preserving intrinsic fluorescent proteins or aqueous-based...
3.
Chen I, Ettel M, Bell P, Huber A, Findeis-Hosey J, Wang W, et al.
Hum Pathol
. 2024 Feb;
144:40-45.
PMID: 38307342
The SWItch/Sucrose Non-Fermentable (SWI/SNF) complex is a multimeric protein involved in transcription regulation and DNA damage repair. SWI/SNF complex abnormalities are observed in approximately 14-34 % of pancreatic ductal adenocarcinomas...
4.
Uccello T, Lesch M, Kintzel S, Gradzewicz L, Lamrous L, Murphy S, et al.
Cell Death Dis
. 2023 Jul;
14(7):470.
PMID: 37495596
Rectal cancer ranks as the second leading cause of cancer-related deaths. Neoadjuvant therapy for rectal cancer patients often results in individuals that respond well to therapy and those that respond...
5.
Najdawi F, Sucipto K, Mistry P, Hennek S, Jayson C, Lin M, et al.
Mod Pathol
. 2023 Feb;
36(6):100124.
PMID: 36841434
Ulcerative colitis is a chronic inflammatory bowel disease that is characterized by a relapsing and remitting course. Assessment of disease activity critically informs treatment decisions. In addition to endoscopic remission,...
6.
Uccello T, Lesch M, Ullman N, Kintzel S, Gradzewicz L, Velagaleti T, et al.
Int J Radiat Oncol Biol Phys
. 2022 Oct;
115(3):733-745.
PMID: 36202180
Purpose: Many solid tumors present with perineural invasion (PNI), and innervation correlates with worsened prognosis. The effects that commonly administered therapies such as radiation therapy (RT) have on PNI status...
7.
Emmrich S, Trapp A, Zakusilo F, Straight M, Ying A, Tyshkovskiy A, et al.
EMBO J
. 2022 Jun;
41(15):e109694.
PMID: 35694726
Naked mole rats (NMRs) are the longest-lived rodents yet their stem cell characteristics remain enigmatic. Here, we comprehensively mapped the NMR hematopoietic landscape and identified unique features likely contributing to...
8.
Klapholz M, Drage M, Srivastava A, Anderson A
J Pathol
. 2022 Feb;
257(2):186-197.
PMID: 35119692
Colorectal carcinoma (CRC) is the second leading cause of cancer mortality worldwide. CRC is stratified into two major groups: microsatellite stable (MSS) and microsatellite instability-high (MSI-H). MSS CRC constitutes the...
9.
Uccello T, Kintzel S, Mills B, Murphy J, Garrett-Larsen J, Battaglia N, et al.
Adv Radiat Oncol
. 2022 Jan;
7(2):100867.
PMID: 35036637
Purpose: Orthotopic tumors more closely recapitulate human cancers than do ectopic models; however, precision targeting of such internal tumors for radiation therapy (RT) without inducing systemic toxicity remains a barrier....
10.
Mills B, Qiu H, Drage M, Chen C, Mathew J, Garrett-Larsen J, et al.
Clin Cancer Res
. 2021 Dec;
28(1):150-162.
PMID: 34862242
Purpose: Stereotactic body radiotherapy (SBRT) is an emerging treatment modality for pancreatic ductal adenocarcinoma (PDAC), which can effectively prime cytotoxic T cells by inducing immunogenic tumor cell death in preclinical...