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Michael G Appiah

Explore the profile of Michael G Appiah including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 190
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Recent Articles
1.
Obeng G, Park E, Appiah M, Kawamoto E, Gaowa A, Shimaoka M
Sci Rep . 2021 Nov; 11(1):21597. PMID: 34732818
The ability of integrins on the cell surface to mediate cell adhesion to the extracellular matrix ligands is regulated by intracellular signaling cascades. During this signaling process, the talin (TLN)...
2.
Appiah M, Park E, Akama Y, Nakamori Y, Kawamoto E, Gaowa A, et al.
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34361061
Sepsis is a sustained systemic inflammatory condition involving multiple organ failures caused by dysregulated immune response to infections. Sepsis induces substantial changes in energy demands at the cellular level leading...
3.
Myint P, Ito A, Appiah M, Obeng G, Darkwah S, Kawamoto E, et al.
Biochem Biophys Rep . 2021 Mar; 26:100977. PMID: 33732908
Irisin, a myokine released from skeletal muscle, has recently been found to act as a ligand for the integrins αVβ5, αVβ1, and α5β1 expressed on mesenchymal cells, thereby playing an...
4.
Darkwah S, Park E, Myint P, Ito A, Appiah M, Obeng G, et al.
Front Cell Dev Biol . 2021 Feb; 9:634853. PMID: 33614663
Extracellular vesicles (EVs) have emerged as key players of intercellular communication and mediate crosstalk between tissues. Metastatic tumors release tumorigenic EVs, capable of pre-conditioning distal sites for organotropic metastasis. Growing...
5.
Park E, Myint P, Appiah M, Worawattananutai P, Inprasit J, Prajuabjinda O, et al.
Biochem Biophys Rep . 2021 Feb; 26:100932. PMID: 33553692
Expression of chemokine receptor CX3CR1 is reportedly restricted to several cell types including natural killer cells, cytotoxic T cells, monocytes, and macrophages. However, its expression and function on exosomes, which...
6.
Park E, Myint P, Ito A, Appiah M, Darkwah S, Kawamoto E, et al.
Front Cell Dev Biol . 2020 Nov; 8:588066. PMID: 33195249
Integrins are transmembrane proteins that mediate cellular adhesion and migration to neighboring cells or the extracellular matrix, which is essential for cells to undertake diverse physiological and pathological pathways. For...
7.
Appiah M, Park E, Darkwah S, Kawamoto E, Akama Y, Gaowa A, et al.
Int J Mol Sci . 2020 Nov; 21(22). PMID: 33182773
Sepsis is a systemic inflammatory disorder induced by a dysregulated immune response to infection resulting in dysfunction of multiple critical organs, including the intestines. Previous studies have reported contrasting results...
8.
Akama Y, Park E, Satoh-Takayama N, Gaowa A, Ito A, Kawamoto E, et al.
Shock . 2020 Aug; 55(3):357-370. PMID: 32826811
Deregulation of the immune system in sepsis plays the central role in the pathogenesis of multiple organ failure including septic lung injury. Group 2 innate lymphoid cells (ILC2s) have emerged...
9.
Park E, Appiah M, Myint P, Gaowa A, Kawamoto E, Shimaoka M
Curr Pharm Des . 2019 Nov; 25(42):4486-4495. PMID: 31738129
Sepsis is the leading cause of death in medical intensive care units, and thus represents a serious healthcare problem worldwide. Sepsis is often caused by the aberrant host responses to...
10.
Darkwah S, Nago N, Appiah M, Myint P, Kawamoto E, Shimaoka M, et al.
Biomedicines . 2019 Jul; 7(3). PMID: 31323786
Sepsis is a systemically dysregulated inflammatory syndrome, in which dendritic cells (DCs) play a critical role in coordinating aberrant immunity. The aim of this study is to shed light on...