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Gideon Obeng

Explore the profile of Gideon Obeng including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 35
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Recent Articles
1.
Mokmued K, Obeng G, Kawamoto E, Caidengbate S, Leangpanich S, Akama Y, et al.
Exp Cell Res . 2024 Jun; 440(2):114146. PMID: 38936759
A microRNA miR-200c-3p is a regulator of epithelial-mesenchymal transition to control adhesion and migration of epithelial and mesenchymal cells. However, little is known about whether miR-200c-3p affects lymphocyte adhesion and...
2.
Obeng G, Park E, Appiah M, Kawamoto E, Gaowa A, Shimaoka M
Sci Rep . 2021 Nov; 11(1):21597. PMID: 34732818
The ability of integrins on the cell surface to mediate cell adhesion to the extracellular matrix ligands is regulated by intracellular signaling cascades. During this signaling process, the talin (TLN)...
3.
Myint P, Ito A, Appiah M, Obeng G, Darkwah S, Kawamoto E, et al.
Biochem Biophys Rep . 2021 Mar; 26:100977. PMID: 33732908
Irisin, a myokine released from skeletal muscle, has recently been found to act as a ligand for the integrins αVβ5, αVβ1, and α5β1 expressed on mesenchymal cells, thereby playing an...
4.
Darkwah S, Park E, Myint P, Ito A, Appiah M, Obeng G, et al.
Front Cell Dev Biol . 2021 Feb; 9:634853. PMID: 33614663
Extracellular vesicles (EVs) have emerged as key players of intercellular communication and mediate crosstalk between tissues. Metastatic tumors release tumorigenic EVs, capable of pre-conditioning distal sites for organotropic metastasis. Growing...
5.
Kawamoto E, Nago N, Okamoto T, Gaowa A, Masui-Ito A, Akama Y, et al.
Biomedicines . 2021 Feb; 9(2). PMID: 33562346
Thrombomodulin is a molecule with anti-coagulant and anti-inflammatory properties. Recently, thrombomodulin was reported to be able to bind extracellular matrix proteins, such as fibronectin and collagen; however, whether thrombomodulin regulates...
6.
Kawamoto E, Nago N, Okamoto T, Gaowa A, Masui-Ito A, Sakakura Y, et al.
Biochem Biophys Res Commun . 2019 Feb; 511(2):312-317. PMID: 30777333
We reported previously that leukocyte β2 integrins (LFA-1 and Mac-1) bind to the serine/threonine-rich domain of thrombomodulin (TM) expressed on vascular endothelial cells (VECs). Recombinant human soluble TM (rhsTM, TMD123)...