Michael E Pichichero
Overview
Explore the profile of Michael E Pichichero including associated specialties, affiliations and a list of published articles.
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206
Citations
3331
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Recent Articles
1.
E Pichichero M, Gonzalez E, Cox A, Thayer T, Bajorski P
J Infect Dis
. 2025 Jan;
PMID: 39797911
Introduction: We sought to explore the variability of antibody responses to multiple vaccines during early life in individual children, assess the trajectory of each child longitudinally, determine the associations of...
2.
Fuji N, Pham M, Kaur R, E Pichichero M
Pediatr Infect Dis J
. 2023 Dec;
43(3):294-300.
PMID: 38048644
Background: Prevention of infections in children vaccinated with 13-valent pneumococcal conjugate vaccine (PCV13) may be less effective against serotype 3 than 19A. Objective: The aim of this study was to...
3.
E Pichichero M, Xu L, Gonzalez E, Pham M, Kaur R
J Infect Dis
. 2023 Nov;
229(6):1856-1865.
PMID: 37992188
Background: Variability in vaccine responsiveness among young children is poorly understood. Methods: Nasopharyngeal secretions were collected in the first weeks of life for measurement of cytokines/chemokines seeking a biomarker, and...
4.
E Pichichero M
Cell Immunol
. 2023 Oct;
393-394:104777.
PMID: 37866234
Vaccinations in early life elicit variable antibody and cellular immune responses, sometimes leaving fully vaccinated children unprotected against life-threatening infectious diseases. Specific immune cell populations and immune networks may have...
5.
Shaffer M, Best K, Tang C, Liang X, Schulz S, Gonzalez E, et al.
mSystems
. 2023 Aug;
8(5):e0066123.
PMID: 37610205
We show that simultaneous study of stool and nasopharyngeal microbiome reveals divergent timing and patterns of maturation, suggesting that local mucosal factors may influence microbiome composition in the gut and...
6.
Bajorski P, Fuji N, Kaur R, E Pichichero M
Pediatrics
. 2023 Jan;
151(2).
PMID: 36618001
Background: Contemporary, quantitative data are needed to inform recommendations and decision-making regarding referral and surgeon endorsement of tympanostomy tube placement in young children with recurrent acute otitis media (AOM). Methods:...
7.
Jones S, Cook K, Holmquist M, Almekinder L, Delaney A, Charles R, et al.
Proteins
. 2022 Sep;
91(2):161-170.
PMID: 36065600
We have determined the 1.8 Å X-ray crystal structure of nonlipidated (i.e., N-terminally truncated) nontypeable Haemophilus influenzae (NTHi; H. influenzae) protein D. Protein D exists on outer membranes of H....
8.
Sharma S, E Pichichero M
Pediatr Allergy Immunol Pulmonol
. 2022 Aug;
26(1):4-10.
PMID: 35927842
Newborns and young children rely on innate immunity to protect against infections until the adaptive immune system matures. Immunization helps facilitate protection, but multiple doses are needed to establish sufficient...
9.
Chapman T, Pham M, Bajorski P, E Pichichero M
Pediatrics
. 2022 Apr;
149(5).
PMID: 35474546
Background: The majority of children are prescribed antibiotics in the first 2 years of life while vaccine-induced immunity develops. Researchers have suggested a negative association of antibiotic use with vaccine-induced...
10.
E Pichichero M, Morris M, Almudevar A
Biomark Appl
. 2022 Jan;
2(1).
PMID: 35005455
Background: 1.1Diagnosis of Acute Otitis Media (AOM) is challenging, resulting in frequent over diagnosis and improper prescription of antibiotics. A serum biomarker of AOM would significantly improve pediatric care for...