Michael E Cox
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Explore the profile of Michael E Cox including associated specialties, affiliations and a list of published articles.
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61
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1622
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Recent Articles
11.
Young O, Webster D, Cox M, Raakjaer J, Blaxekjaer L, Einarsson N, et al.
Proc Natl Acad Sci U S A
. 2018 Aug;
115(37):9065-9073.
PMID: 30139919
In fisheries management-as in environmental governance more generally-regulatory arrangements that are thought to be helpful in some contexts frequently become panaceas or, in other words, simple formulaic policy prescriptions believed...
12.
Gordon J, Buonerba C, Pond G, Crona D, Gillessen S, Lucarelli G, et al.
Oncotarget
. 2018 May;
9(28):19861-19873.
PMID: 29731989
Background: Statins may potentiate the effects of anti-hormonal agents for metastatic castration-resistant prostate cancer (mCRPC) through further disruption of essential steroidogenic processes. We investigated the effects of statin use on...
13.
Sharma M, Levenson C, Browning J, Becker E, Clements I, Castella P, et al.
Front Pharmacol
. 2018 Mar;
9:200.
PMID: 29593534
Cyclic adenosine monophosphate phosphodiesterases (PDEs) regulate pro-inflammatory cytokine production. One isoform, PDE4, is overactive in chronic relapsing inflammatory skin diseases: psoriasis and eczema/atopic dermatitis, and in several cancers. East Indian...
14.
Tam K, Hui D, Lee W, Dong M, Tombe T, Jiao I, et al.
Sci Rep
. 2017 Sep;
7(1):11501.
PMID: 28904399
Prostate cancer (PCa) is among the most commonly-occurring cancers worldwide and a leader in cancer-related deaths. Local non-invasive PCa is highly treatable but limited treatment options exist for those with...
15.
Butler M, Roshan-Moniri M, Hsing M, Lau D, Kim A, Yen P, et al.
Oncotarget
. 2017 May;
8(26):42438-42454.
PMID: 28465491
Genomic alterations involving translocations of the ETS-related gene ERG occur in approximately half of prostate cancer cases. These alterations result in aberrant, androgen-regulated production of ERG protein variants that directly...
16.
Lee A, Li Y, Xie N, Gleave M, Cox M, Collins C, et al.
Oncotarget
. 2017 Apr;
8(17):27966-27975.
PMID: 28427194
Although potent androgen receptor pathway inhibitors (ARPI) improve overall survival of metastatic prostate cancer patients, treatment-induced neuroendocrine prostate cancer (t-NEPC) as a consequence of the selection pressures of ARPI is...
17.
East Indian Sandalwood Oil (EISO) Alleviates Inflammatory and Proliferative Pathologies of Psoriasis
Sharma M, Levenson C, Clements I, Castella P, Gebauer K, Cox M
Front Pharmacol
. 2017 Apr;
8:125.
PMID: 28360856
Psoriasis, a chronic inflammatory skin disease marked by hyper proliferation and aberrant differentiation of keratinocytes, affects 2-3% of the world's population. Research into the pathogenesis of psoriasis has been hampered...
18.
Lubik A, Nouri M, Truong S, Ghaffari M, Adomat H, Corey E, et al.
Int J Cancer
. 2016 Sep;
140(2):358-369.
PMID: 27672740
Despite the substantial benefit of androgen deprivation therapy (ADT) for metastatic prostate cancer, patients often progress to castration-resistant disease (CRPC) that is more difficult to treat. CRPC is associated with...
19.
Labrecque M, Takhar M, Nason R, Santacruz S, Tam K, Massah S, et al.
Oncotarget
. 2016 Mar;
7(17):24284-302.
PMID: 27015368
Loss of tumor suppressor proteins, such as the retinoblastoma protein (Rb), results in tumor progression and metastasis. Metastasis is facilitated by low oxygen availability within the tumor that is detected...
20.
Esmaeilsabzali H, Beischlag T, Cox M, Dechev N, Parameswaran A, Park E
Biomed Microdevices
. 2016 Feb;
18(1):22.
PMID: 26876965
The quantitative and qualitative analysis of circulating tumor cells (CTCs) has the potential to improve the clinical management of several cancers, including prostate cancer. As such, there is much interest...