Michael E Bregenzer
Overview
Explore the profile of Michael E Bregenzer including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
7
Citations
210
Followers
0
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Recent Articles
1.
Horst E, Bregenzer M, Mehta P, Snyder C, Repetto T, Yang-Hartwich Y, et al.
Acta Biomater
. 2021 May;
132:401-420.
PMID: 33940195
Intractable human diseases such as cancers, are context dependent, unique to both the individual patient and to the specific tumor microenvironment. However, conventional cancer treatments are often nonspecific, targeting global...
2.
Bregenzer M, Horst E, Mehta P, Novak C, Repetto T, Snyder C, et al.
Ann Transl Med
. 2020 Feb;
7(Suppl 8):S262.
PMID: 32015981
No abstract available.
3.
Bregenzer M, Davis C, Horst E, Mehta P, Novak C, Raghavan S, et al.
J Vis Exp
. 2019 Jul;
(149).
PMID: 31329171
In this protocol, we outline the procedure for generation of tumor spheroids within 384-well hanging droplets to allow for high-throughput screening of anti-cancer therapeutics in a physiologically representative microenvironment. We...
4.
Bregenzer M, Horst E, Mehta P, Novak C, Repetto T, Mehta G
Cancers (Basel)
. 2019 Jul;
11(7).
PMID: 31323899
Ovarian cancer is an extremely lethal gynecologic disease; with the high-grade serous subtype predominantly associated with poor survival rates. Lack of early diagnostic biomarkers and prevalence of post-treatment recurrence, present...
5.
Bregenzer M, Horst E, Mehta P, Novak C, Raghavan S, Snyder C, et al.
PLoS One
. 2019 May;
14(5):e0216564.
PMID: 31075118
Tumors are not merely cancerous cells that undergo mindless proliferation. Rather, they are highly organized and interconnected organ systems. Tumor cells reside in complex microenvironments in which they are subjected...
6.
Raghavan S, Mehta P, Ward M, Bregenzer M, Fleck E, Tan L, et al.
Clin Cancer Res
. 2017 Aug;
23(22):6934-6945.
PMID: 28814433
Chemoresistant ovarian cancers grow in suspension within the ascites fluid. To screen the effect of chemotherapeutics and biologics on resistant ovarian cancers with a personalized basis, we developed a 3D...
7.
Heintz K, Bregenzer M, Mantle J, Lee K, West J, Slater J
Adv Healthc Mater
. 2016 May;
5(17):2153-60.
PMID: 27239785
A laser-based hydrogel degradation technique is developed that allows for local control over hydrogel porosity, fabrication of 3D vascular-derived, biomimetic, hydrogel-embedded microfluidic networks, and generation of two intertwining, yet independent,...