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Michael Duszenko

Explore the profile of Michael Duszenko including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 4525
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Recent Articles
1.
Uzcategui N, Gucer S, Richter C, Speidel A, Zirdum E, Duszenko M, et al.
Front Immunol . 2023 Oct; 14:1253648. PMID: 37781403
Introduction: Invasion of the central nervous system (CNS) is the most serious consequence of infection, which causes sleeping sickness. Recent experimental data have revealed some more insights into the disease...
2.
Speidel A, Theile M, Pfeiffer L, Herrmann A, Figarella K, Ishikawa H, et al.
iScience . 2022 Mar; 25(4):104014. PMID: 35313698
is the causative agent of human African trypanosomiasis. The parasite transmigrates from blood vessels across the choroid plexus epithelium to enter the central nervous system, a process that leads to...
3.
Dreischer P, Duszenko M, Stein J, Wieder T
Cells . 2022 Feb; 11(3). PMID: 35159312
Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin, specializing in the transport of oxygen. With a total number of approximately 25 trillion cells per individual, the erythrocyte is the...
4.
Duszenko M, Frohlich N, Kaupp A, Garaschuk O
BMC Med Educ . 2022 Jan; 22(1):3. PMID: 34980108
Background: The social distancing and suspension of on-campus learning, imposed by the COVID-19 pandemic, are likely to influence medical training for months if not years. Thus, there is a need...
5.
Lushchak V, Duszenko M, Gospodaryov D, Garaschuk O
Antioxidants (Basel) . 2021 Nov; 10(11). PMID: 34829586
Neural tissue is one of the main oxygen consumers in the mammalian body, and a plentitude of metabolic as well as signaling processes within the brain is accompanied by the...
6.
Figarella K, Wolburg H, Garaschuk O, Duszenko M
Biol Rev Camb Philos Soc . 2019 Nov; 95(2):333-349. PMID: 31682077
Involvement of the central nervous system (CNS) is the most severe consequence of some parasitic infections. Protozoal infections comprise a group of diseases that together affect billions of people worldwide...
7.
Mudogo C, Falke S, Brognaro H, Duszenko M, Betzel C
Traffic . 2019 Oct; 21(2):220-230. PMID: 31664760
Liquid-liquid phase separation (LLPS) in cells is known as a complex physicochemical process causing the formation of membrane-less organelles (MLOs). Cells have well-defined different membrane-surrounded organelles like mitochondria, endoplasmic reticulum,...
8.
Figarella K, Uzcategui N, Duszenko M
Methods Mol Biol . 2019 Aug; 2034:149-161. PMID: 31392683
An extensive number of parasites are able to invade the central nervous system (CNS) and cause a plethora of pathologies. Microglia, the resident macrophages of nervous tissue, are responsible for...
9.
Figarella K, Uzcategui N, Mogk S, Wild K, Fallier-Becker P, Neher J, et al.
Sci Rep . 2018 Oct; 8(1):15002. PMID: 30302029
The flagellated parasite Trypanosoma brucei is the causative agent of Human African Trypanosomiasis (HAT). By a mechanism not well understood yet, trypanosomes enter the central nervous system (CNS), invade the...
10.
Mudogo C, Werner S, Mogk S, Betzel C, Duszenko M
Acta Trop . 2018 Aug; 188:34-40. PMID: 30153427
Trypanosoma brucei, a flagellated protozoan causing the deadly tropical disease Human African Trypanosomiasis (HAT), affects people in sub-Saharan Africa. HAT therapy relies upon drugs which use is limited by toxicity...